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Search the entire catalog of SABiosciences products by gene name, key word, or RefSeq number. To learn more about all of these products, visit our Send an Email to Technical Support.

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  2. Use Gene Symbols, key words, or RefSeq Accession Numbers for your gene of interest to find the catalog numbers for the corresponding products. To learn how to get RefSeq Accession Numbers, click here.
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  4. Click 'Submit'.
Species:
Gene Name, symbol, description:      RefSeq Number:   
All Product Lines
RT≤ Profilerô PCR Array Pathway-Focused qRT-PCR Based Expression Profiling
RT≤ qPCR Primer Assay Gene-Specific Primers for qRT-PCR, Genome-Wide Availability
Cignalô Pathway Reporter Assays Cell-Based Assays for Rapidly Analyzing Pathway Signaling Activity
miScript miRNA PCR Array miScript miRNA PCR Array
Multi-Analyte Profiler ELISArray Kits Analyze 12 Cytokines or Chemokines Simultaneously Using ELISA
Single Analyte ELISArray Kits High Performance ELISA with the Best Possible Antibodies
EpiTect Methyl II PCR Arrays Pathway-Focused PCR Based DNA Methylation Analysis
EpiTect Methyl II PCR Primer Assay PCR Assays for DNA Methylation Analysis, Genome-Wide Availability
SureSilencingô shRNA Gene-Specific Plasmid-Based RNA Interference, Genome-Wide Availability
EpiTect ChIP qPCR Arrays Pathway-Focused qPCR Based Histone Modifications Analysis
        
Search Result: 54 gene(s) found matching 'INS'
Gene Symbol: INS (Human)Other Aliases: IDDM2, ILPR, IRDN, MODY10
Refseq IDs: NM_000207, NM_001185097, NM_001185098
Description: Insulin
After removal of the precursor signal peptide, proinsulin is post-translationally cleaved into two chains (peptide A and peptide B) that are covalently linked via two disulfide bonds. Binding of this mature form of insulin to the insulin receptor (INSR) stimulates glucose uptake. A variety of mutant alleles with changes in the coding region have been identified. There is a read-through gene, INS-IGF2, which overlaps with this gene at the 5' region and with the IGF2 gene at the 3' region.
Products:
 RT≤ Profilerô PCR Array15 products

Gene Symbol: AQP12B (Human)Other Aliases: INSSA3
Refseq IDs: NM_001102467, ENST00000407834, ENST00000413999, ENST00000414322, ENST00000452886, ENST00000459806
Description: Aquaporin 12B
Products:
 RT≤ Profilerô PCR ArrayInquire

Gene Symbol: IDE (Human)Other Aliases: INSULYSIN
Refseq IDs: NM_004969, NM_001165946, XM_005269766, XM_005269767, XM_005269768, XM_005269769, XM_005269770, ENST00000265986, ENST00000371581, ENST00000436178, ENST00000462988, ENST00000463640, ENST00000478361, ENST00000492362, ENST00000496903
Description: Insulin-degrading enzyme
This gene may belong to a protease family responsible for intercellular peptide signalling. Though its role in the cellular processing of insulin has not yet been defined, insulin-degrading enzyme is thought to be involved in the termination of the insulin response.
Products:
 RT≤ Profilerô PCR Array2 products

Gene Symbol: INS-IGF2 (Human)Other Aliases: INSIGF
Refseq IDs: NM_001042376, NR_003512, ENST00000356578, ENST00000397270, ENST00000476874, ENST00000481781
Description: INS-IGF2 readthrough
Products:
 RT≤ Profilerô PCR ArrayInquire

Gene Symbol: INSC (Human)Other Aliases:
Refseq IDs: NM_001031853, NM_001042536, NM_001278313, NM_001278314, NM_001278315, NM_001278316, XM_005252911, ENST00000379554, ENST00000379556, ENST00000424273, ENST00000447214, ENST00000525218, ENST00000526102, ENST00000528567, ENST00000530161
Description: Inscuteable homolog (Drosophila)
Products:
 RT≤ Profilerô PCR ArrayInquire

Gene Symbol: INSIG1 (Human)Other Aliases: CL-6, CL6
Refseq IDs: NM_005542, NM_198337, NM_198336, XM_005249542, XM_005249543, ENST00000340368, ENST00000342407, ENST00000344756, ENST00000425172, ENST00000468307, ENST00000476756
Description: Insulin induced gene 1
Oxysterols regulate cholesterol homeostasis through liver X receptor (LXR) and sterol regulatory element-binding protein (SREBP) mediated signaling pathway. This gene is an insulin-induced gene. It encodes an endoplasmic reticulum (ER) membrane protein that plays a critical role in regulating cholesterol concentrations in cells. This protein binds to the sterol-sensing domains of SREBP cleavage-activating protein (SCAP) and HMG CoA reductase, and is essential for the sterol-mediated trafficking of the two proteins. Alternatively spliced transcript variants encoding distinct isoforms have been observed.
Products:
 RT≤ Profilerô PCR Array3 products

Gene Symbol: INSIG2 (Human)Other Aliases:
Refseq IDs: NM_016133, XM_005263690, XM_005263691, ENST00000245787, ENST00000411929, ENST00000467223, ENST00000471186, ENST00000479999, ENST00000485520, ENST00000488995
Description: Insulin induced gene 2
The protein encoded by this gene is highly similar to the protein product encoded by gene INSIG1. Both INSIG1 protein and this protein are endoplasmic reticulum proteins that block the processing of sterol regulatory element binding proteins (SREBPs) by binding to SREBP cleavage-activating protein (SCAP), and thus prevent SCAP from escorting SREBPs to the Golgi.
Products:
 RT≤ Profilerô PCR Array3 products

Gene Symbol: INSL3 (Human)Other Aliases: RLF, RLNL, ley-I-L
Refseq IDs: NM_005543, NM_001265587
Description: Insulin-like 3 (Leydig cell)
The protein encoded by this gene is an insulin like hormone produced mainly in gonadal tissues in males and females. Studies of the mouse counterpart suggest that this gene may be involved in the development of urogenital tract and female fertility. It may also act as a hormone to regulate growth and differentiation of gubernaculum, and thus mediating intra-abdominal testicular descent. The mutations in this gene may lead to, but not a frequent cause of, cryptorchidism.
Products:
 RT≤ Profilerô PCR Array1 products

Gene Symbol: INSL4 (Human)Other Aliases: EPIL, PLACENTIN
Refseq IDs: NM_002195
Description: Insulin-like 4 (placenta)
INSL4 encodes the insulin-like 4 protein, a member of the insulin superfamily. INSL4 encodes a precursor that undergoes post-translational cleavage to produce 3 polypeptide chains, A-C, that form tertiary structures composed of either all three chains, or just the A and B chains. Expression of INSL4 products occurs within the early placental cytotrophoblast and syncytiotrophoblast.
Products:
 RT≤ Profilerô PCR ArrayInquire

Gene Symbol: INSL5 (Human)Other Aliases: PRO182, UNQ156
Refseq IDs: NM_005478
Description: Insulin-like 5
The protein encoded by this gene contains a classical signature of the insulin superfamily and is highly similar to relaxin 3 (RLN3/INSL7).
Products:
 RT≤ Profilerô PCR ArrayInquire

Gene Symbol: INSL6 (Human)Other Aliases: RIF1
Refseq IDs: NM_007179, ENST00000381641, ENST00000510407
Description: Insulin-like 6
The protein encoded by this gene contains a classical signature of the insulin superfamily and is significantly similar to relaxin and relaxin-like factor. This gene is preferentially expressed in testis. Its expression in testis is restricted to interstitial cells surrounding seminiferous tubules, which suggests a role in sperm development and fertilization.
Products:
 RT≤ Profilerô PCR ArrayInquire

Gene Symbol: INSM1 (Human)Other Aliases: IA-1, IA1
Refseq IDs: NM_002196
Description: Insulinoma-associated 1
Insulinoma-associated 1 (INSM1) gene is intronless and encodes a protein containing both a zinc finger DNA-binding domain and a putative prohormone domain. This gene is a sensitive marker for neuroendocrine differentiation of human lung tumors.
Products:
 RT≤ Profilerô PCR ArrayInquire

Gene Symbol: INSM2 (Human)Other Aliases: IA-6, IA6, mlt1
Refseq IDs: NM_032594
Description: Insulinoma-associated 2
Products:
 RT≤ Profilerô PCR ArrayInquire

Gene Symbol: INSR (Human)Other Aliases: CD220, HHF5
Refseq IDs: NM_000208, NM_001079817, XM_005259552, XM_005259553, XM_005259554, ENST00000302850, ENST00000341500, ENST00000593970, ENST00000597211, ENST00000598216, ENST00000600492, ENST00000601099
Description: Insulin receptor
After removal of the precursor signal peptide, the insulin receptor precursor is post-translationally cleaved into two chains (alpha and beta) that are covalently linked. Binding of insulin to the insulin receptor (INSR) stimulates glucose uptake.
Products:
 RT≤ Profilerô PCR Array11 products

Gene Symbol: INSRR (Human)Other Aliases: IRR
Refseq IDs: NM_014215
Description: Insulin receptor-related receptor
Products:
 RT≤ Profilerô PCR Array1 products

Gene Symbol: IP6K3 (Human)Other Aliases: IHPK3, INSP6K3
Refseq IDs: NM_054111, NM_001142883, XM_005248842, XM_005248843
Description: Inositol hexakisphosphate kinase 3
This gene encodes a protein that belongs to the inositol phosphokinase (IPK) family. This protein is likely responsible for the conversion of inositol hexakisphosphate (InsP6) to diphosphoinositol pentakisphosphate (InsP7/PP-InsP5). It may also convert 1,3,4,5,6-pentakisphosphate (InsP5) to PP-InsP4.
Products:
 RT≤ Profilerô PCR ArrayInquire

Gene Symbol: IPPK (Human)Other Aliases: C9orf12, INSP5K2, IP5K, IPK1, bA476B13.1
Refseq IDs: NM_022755, XM_005252134, ENST00000287996, ENST00000375522, ENST00000486841
Description: Inositol 1,3,4,5,6-pentakisphosphate 2-kinase
Products:
 RT≤ Profilerô PCR ArrayInquire

Gene Symbol: ITPR1 (Human)Other Aliases: INSP3R1, IP3R, IP3R1, SCA15, SCA16, SCA29
Refseq IDs: NM_002222, NM_001099952, NM_001168272, XM_005265108, XM_005265109, XM_005265110, ENST00000302640, ENST00000354582, ENST00000357086, ENST00000423119, ENST00000443694, ENST00000456211, ENST00000463980, ENST00000467056, ENST00000467545, ENST00000472205, ENST00000477577, ENST00000478515, ENST00000479831, ENST00000481415, ENST00000487016, ENST00000490572, ENST00000491868, ENST00000493491, ENST00000494681, ENST00000544951
Description: Inositol 1,4,5-trisphosphate receptor, type 1
Products:
 RT≤ Profilerô PCR Array5 products

Gene Symbol: SYCN (Human)Other Aliases: INSSA1, SYL
Refseq IDs: NM_001080468
Description: Syncollin
Products:
 RT≤ Profilerô PCR ArrayInquire

Gene Symbol: RXFP4 (Human)Other Aliases: GPCR142, GPR100, RLN3R2, RXFPR4
Refseq IDs: NM_181885
Description: Relaxin/insulin-like family peptide receptor 4
GPR100 is a member of the rhodopsin family of G protein-coupled receptors (GPRs) (Fredriksson et al., 2003).[supplied by OMIM]
Products:
 RT≤ Profilerô PCR Array1 products

Gene Symbol: RXFP3 (Human)Other Aliases: GPCR135, RLN3R1, RXFPR3, SALPR
Refseq IDs: NM_016568
Description: Relaxin/insulin-like family peptide receptor 3
Products:
 RT≤ Profilerô PCR Array1 products

Gene Symbol: RXFP2 (Human)Other Aliases: GPR106, GREAT, INSL3R, LGR8, LGR8.1, RXFPR2
Refseq IDs: NM_130806, NM_001166058
Description: Relaxin/insulin-like family peptide receptor 2
The receptors for glycoprotein hormones such as follicle-stimulating hormone (FSH; see MIM 136530) and thyroid-stimulating hormone (TSH; see MIM 188540) are G protein-coupled, 7-transmembrane receptors (GPCRs) with large N-terminal extracellular domains. Leucine-rich repeat (LRR)-containing GPCRs (LGRs) form a subgroup of the GPCR superfamily.[supplied by OMIM]
Products:
 RT≤ Profilerô PCR Array1 products

Gene Symbol: RXFP1 (Human)Other Aliases: LGR7, RXFPR1
Refseq IDs: NM_021634, NM_001253727, NM_001253728, NM_001253729, NM_001253730, NM_001253732, NM_001253733, NR_045579, NR_045580, NR_045581, NR_045582, NR_045583, NR_045584, ENST00000307765, ENST00000342048, ENST00000343542, ENST00000423548, ENST00000448688, ENST00000460056, ENST00000470033, ENST00000471616, ENST00000472969, ENST00000484785
Description: Relaxin/insulin-like family peptide receptor 1
Products:
 RT≤ Profilerô PCR Array1 products

Gene Symbol: RMI2 (Human)Other Aliases: BLAP18, C16orf75
Refseq IDs: NM_152308, ENST00000312499, ENST00000381820, ENST00000572173, ENST00000572992, ENST00000573910, ENST00000576027
Description: RMI2, RecQ mediated genome instability 2, homolog (S. cerevisiae)
Products:
 RT≤ Profilerô PCR ArrayInquire

Gene Symbol: RMI1 (Human)Other Aliases: BLAP75, C9orf76, FAAP75, RP11-346I8.1
Refseq IDs: NM_024945, XM_005252211, XM_005252212, XM_005252213, XM_005252214, XM_005252215, XM_005252216
Description: RMI1, RecQ mediated genome instability 1, homolog (S. cerevisiae)
Products:
 RT≤ Profilerô PCR ArrayInquire

Gene Symbol: RLN3 (Human)Other Aliases: H3, RXN3, ZINS4, insl7
Refseq IDs: NM_080864
Description: Relaxin 3
Relaxins are known endocrine and autocrine/paracrine hormones, belonging to the insulin gene superfamily. In the human there are three non-allelic relaxin genes, RLN1, RLN2 and RLN3. RLN1 and RLN2 share high sequence homology. Relaxin is produced by the ovary, and targets the mammalian reproductive system to ripen the cervix, elongate the pubic symphysis and inhibit uterine contraction. It may have additional roles in enhancing sperm motility, regulating blood pressure, controlling heart rate and releasing oxytocin and vasopressin. The protein encoded by this gene is a member of the relaxin family. The active form of the encoded protein consists of an A chain and a B chain but their cleavage sites are not definitely described yet. It may play a role in neuropeptide signaling processes.
Products:
 RT≤ Profilerô PCR ArrayInquire

Gene Symbol: MMP24 (Human)Other Aliases: MMP-24, MMP25, MT-MMP 5, MT-MMP5, MT5-MMP, MT5MMP, MTMMP5
Refseq IDs: NM_006690
Description: Matrix metallopeptidase 24 (membrane-inserted)
Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. However, the protein encoded by this gene is a member of the membrane-type MMP (MT-MMP) subfamily; each member of this subfamily contains a potential transmembrane domain suggesting that these proteins are expressed at the cell surface rather than secreted. This protein activates MMP2 by cleavage. The gene has previously been referred to as MMP25 but has been renamed MMP24.
Products:
 RT≤ Profilerô PCR Array1 products

Gene Symbol: MMP17 (Human)Other Aliases: MT4-MMP
Refseq IDs: NM_016155, ENST00000360564, ENST00000534865, ENST00000535004, ENST00000535182, ENST00000535271, ENST00000535291, ENST00000537848, ENST00000542142, ENST00000542648, ENST00000545671, ENST00000545790
Description: Matrix metallopeptidase 17 (membrane-inserted)
Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. The protein encoded by this gene is considered a member of the membrane-type MMP (MT-MMP) subfamily. However, this protein is unique among the MT-MMP's in that it is a GPI-anchored protein rather than a transmembrane protein. The protein activates MMP-2 by cleavage.
Products:
 RT≤ Profilerô PCR ArrayInquire

Gene Symbol: MMP16 (Human)Other Aliases: C8orf57, MMP-X2, MT-MMP2, MT-MMP3, MT3-MMP
Refseq IDs: NM_005941, NM_022564, XM_005250921, ENST00000286614, ENST00000520568, ENST00000522726, ENST00000544227
Description: Matrix metallopeptidase 16 (membrane-inserted)
Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. This gene produces at least two transcripts, one which encodes a membrane-bound form and another a soluble form of the protein. Both forms of the protein activate MMP2 by cleavage. This gene was once referred to as MT-MMP2, but was renamed as MT-MMP3 or MMP16.
Products:
 RT≤ Profilerô PCR Array2 products

Gene Symbol: MMP15 (Human)Other Aliases: MT2-MMP, MTMMP2, SMCP-2
Refseq IDs: NM_002428
Description: Matrix metallopeptidase 15 (membrane-inserted)
Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. However, the protein encoded by this gene is a member of the membrane-type MMP (MT-MMP) subfamily; each member of this subfamily contains a potential transmembrane domain suggesting that these proteins are expressed at the cell surface rather than secreted.
Products:
 RT≤ Profilerô PCR Array2 products

Gene Symbol: MMP14 (Human)Other Aliases: MMP-14, MMP-X1, MT-MMP, MT-MMP 1, MT1-MMP, MT1MMP, MTMMP1, WNCHRS
Refseq IDs: NM_004995, ENST00000311852, ENST00000547074, ENST00000547279, ENST00000547596, ENST00000548162, ENST00000548761
Description: Matrix metallopeptidase 14 (membrane-inserted)
Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. However, the protein encoded by this gene is a member of the membrane-type MMP (MT-MMP) subfamily; each member of this subfamily contains a potential transmembrane domain suggesting that these proteins are expressed at the cell surface rather than secreted. This protein activates MMP2 protein, and this activity may be involved in tumor invasion.
Products:
 RT≤ Profilerô PCR Array4 products

Gene Symbol: KDR (Human)Other Aliases: CD309, FLK1, VEGFR, VEGFR2
Refseq IDs: NM_002253, ENST00000263923, ENST00000509309, ENST00000512566
Description: Kinase insert domain receptor (a type III receptor tyrosine kinase)
Products:
 RT≤ Profilerô PCR Array13 products

Gene Symbol: IRS4 (Human)Other Aliases: IRS-4, PY160
Refseq IDs: NM_003604, XM_005262220
Description: Insulin receptor substrate 4
IRS4 encodes the insulin receptor substrate 4, a cytoplasmic protein that contains many potential tyrosine and serine/threonine phosphorylation sites. Tyrosine-phosphorylated IRS4 protein has been shown to associate with cytoplasmic signalling molecules that contain SH2 domains. The IRS4 protein is phosphorylated by the insulin receptor tyrosine kinase upon receptor stimulation..
Products:
 RT≤ Profilerô PCR Array2 products

Gene Symbol: IRS2 (Human)Other Aliases: IRS-2
Refseq IDs: NM_003749
Description: Insulin receptor substrate 2
This gene encodes the insulin receptor substrate 2, a cytoplasmic signaling molecule that mediates effects of insulin, insulin-like growth factor 1, and other cytokines by acting as a molecular adaptor between diverse receptor tyrosine kinases and downstream effectors. The product of this gene is phosphorylated by the insulin receptor tyrosine kinase upon receptor stimulation, as well as by an interleukin 4 receptor-associated kinase in response to IL4 treatment.
Products:
 RT≤ Profilerô PCR Array6 products

Gene Symbol: IRS1 (Human)Other Aliases: HIRS-1
Refseq IDs: NM_005544, XM_005246534, ENST00000305123, ENST00000498335
Description: Insulin receptor substrate 1
Products:
 RT≤ Profilerô PCR Array10 products

Gene Symbol: IGFBPL1 (Human)Other Aliases: IGFBP-RP4, IGFBPRP4, bA113O24.1
Refseq IDs: NM_001007563
Description: Insulin-like growth factor binding protein-like 1
Products:
 RT≤ Profilerô PCR ArrayInquire

Gene Symbol: IGFBP7 (Human)Other Aliases: AGM, FSTL2, IBP-7, IGFBP-7, IGFBP-7v, IGFBPRP1, MAC25, PSF, RAMSVPS, TAF
Refseq IDs: NM_001553, NM_001253835, ENST00000295666, ENST00000512512, ENST00000514062, ENST00000537922
Description: Insulin-like growth factor binding protein 7
Products:
 RT≤ Profilerô PCR Array2 products

Gene Symbol: IGFBP6 (Human)Other Aliases: IBP6
Refseq IDs: NM_002178, ENST00000301464, ENST00000548176, ENST00000548547, ENST00000549628
Description: Insulin-like growth factor binding protein 6
Products:
 RT≤ Profilerô PCR ArrayInquire

Gene Symbol: IGFBP5 (Human)Other Aliases: IBP5
Refseq IDs: NM_000599, ENST00000233813, ENST00000449583, ENST00000486341
Description: Insulin-like growth factor binding protein 5
Products:
 RT≤ Profilerô PCR Array9 products

Gene Symbol: IGFBP4 (Human)Other Aliases: BP-4, HT29-IGFBP, IBP4, IGFBP-4
Refseq IDs: NM_001552
Description: Insulin-like growth factor binding protein 4
This gene is a member of the insulin-like growth factor binding protein (IGFBP) family and encodes a protein with an IGFBP domain and a thyroglobulin type-I domain. The protein binds both insulin-like growth factors (IGFs) I and II and circulates in the plasma in both glycosylated and non-glycosylated forms. Binding of this protein prolongs the half-life of the IGFs and alters their interaction with cell surface receptors.
Products:
 RT≤ Profilerô PCR Array2 products

Gene Symbol: IGFBP3 (Human)Other Aliases: BP-53, IBP3
Refseq IDs: NM_000598, NM_001013398, XM_005249743, ENST00000275521, ENST00000381083, ENST00000381086, ENST00000417621, ENST00000428530, ENST00000448817, ENST00000460209, ENST00000460477, ENST00000465642
Description: Insulin-like growth factor binding protein 3
This gene is a member of the insulin-like growth factor binding protein (IGFBP) family and encodes a protein with an IGFBP domain and a thyroglobulin type-I domain. The protein forms a ternary complex with insulin-like growth factor acid-labile subunit (IGFALS) and either insulin-like growth factor (IGF) I or II. In this form, it circulates in the plasma, prolonging the half-life of IGFs and altering their interaction with cell surface receptors. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
Products:
 RT≤ Profilerô PCR Array13 products

Gene Symbol: IGFBP2 (Human)Other Aliases: IBP2, IGF-BP53
Refseq IDs: NM_000597, XM_005246528, ENST00000233809, ENST00000434997, ENST00000436812, ENST00000456764, ENST00000490362
Description: Insulin-like growth factor binding protein 2, 36kDa
Products:
 RT≤ Profilerô PCR Array1 products

Gene Symbol: IGFBP1 (Human)Other Aliases: AFBP, IBP1, IGF-BP25, PP12, hIGFBP-1
Refseq IDs: NM_000596
Description: Insulin-like growth factor binding protein 1
This gene is a member of the insulin-like growth factor binding protein (IGFBP) family and encodes a protein with an IGFBP domain and a thyroglobulin type-I domain. The protein binds both insulin-like growth factors (IGFs) I and II and circulates in the plasma. Binding of this protein prolongs the half-life of the IGFs and alters their interaction with cell surface receptors. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
Products:
 RT≤ Profilerô PCR Array6 products

Gene Symbol: IGFALS (Human)Other Aliases: ALS
Refseq IDs: NM_004970, NM_001146006, NR_027389, ENST00000215539, ENST00000415638, ENST00000568221
Description: Insulin-like growth factor binding protein, acid labile subunit
Products:
 RT≤ Profilerô PCR Array1 products

Gene Symbol: IGF2R (Human)Other Aliases: CD222, CIMPR, M6P-R, MPR1, MPRI
Refseq IDs: NM_000876, ENST00000356956, ENST00000464636, ENST00000475584, ENST00000475834, ENST00000487607
Description: Insulin-like growth factor 2 receptor
CD222 is a 250kDa transmembrane protein with a short cytoplasmic tail containing an internalization signal. CD222 was originally identified as a receptor for IGFII and M6P-containing proteins (e.g. lysosomal hydrolases). Lysosomal enzymes are sorted to lysosomes via CD222 either from the Golgi, where the enzymes acquire M6P, or from the extracellular space. The majority of CD222 molecules (approximately 90-95%) are located intracellularly, only 5-10% is present on the cell membrane. The internalization rate seems to be enhanced by ligand induced dimerization of CD222 as well as by phosphorylation of its cytoplasmic serine. CD222 is also a receptor for TGFbeta latency associated peptide (LAP), proliferin and may bind several molecules independently of M6P, including plasminogen, CD87 or retinoic acid. It is involved in activation of latent TGFbeta.
Products:
 RT≤ Profilerô PCR Array3 products

Gene Symbol: IGF2BP3 (Human)Other Aliases: CT98, IMP-3, IMP3, KOC1, VICKZ3
Refseq IDs: NM_006547, ENST00000258729, ENST00000421467, ENST00000465058, ENST00000466809, ENST00000467592, ENST00000468005, ENST00000468263, ENST00000469723, ENST00000474105, ENST00000476938, ENST00000479504, ENST00000480547, ENST00000491719, ENST00000492771, ENST00000495009, ENST00000497563, ENST00000498363
Description: Insulin-like growth factor 2 mRNA binding protein 3
The protein encoded by this gene is primarily found in the nucleolus, where it can bind to the 5' UTR of the insulin-like growth factor II leader 3 mRNA and may repress translation of insulin-like growth factor II during late development. The encoded protein contains several KH domains, which are important in RNA binding and are known to be involved in RNA synthesis and metabolism. A pseudogene exists on chromosome 7, and there are putative pseudogenes on other chromosomes.
Products:
 RT≤ Profilerô PCR Array2 products

Gene Symbol: IGF2BP2 (Human)Other Aliases: IMP-2, IMP2, VICKZ2, p62
Refseq IDs: NM_006548, NM_001007225, XM_005247073, XM_005247074, XM_005247075, ENST00000346192, ENST00000382199, ENST00000421047, ENST00000457616, ENST00000461957, ENST00000464166, ENST00000466214, ENST00000466476, ENST00000493302, ENST00000494906, ENST00000496495
Description: Insulin-like growth factor 2 mRNA binding protein 2
This gene encodes a member of the IGF-II mRNA-binding protein (IMP) family. The protein encoded by this gene contains several four KH domains and two RRM domains. It functions by binding to the 5' UTR of the insulin-like growth factor 2 (IGF2) mRNA and regulating IGF2 translation. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
Products:
 RT≤ Profilerô PCR ArrayInquire

Gene Symbol: IGF2BP1 (Human)Other Aliases: CRD-BP, CRDBP, IMP-1, IMP1, VICKZ1, ZBP1
Refseq IDs: NM_006546, NM_001160423, XM_005256955, ENST00000290341, ENST00000431824, ENST00000499130, ENST00000505562, ENST00000510023, ENST00000515586
Description: Insulin-like growth factor 2 mRNA binding protein 1
This gene encodes a member of the IGF-II mRNA-binding protein (IMP) family. The protein encoded by this gene contains four K homology domains and two RNA recognition motifs. It functions by binding to the 5' UTR of the insulin-like growth factor 2 (IGF2) mRNA and regulating IGF2 translation.
Products:
 RT≤ Profilerô PCR Array2 products

Gene Symbol: IGF2-AS (Human)Other Aliases: IGF2-AS1, IGF2AS, PEG8
Refseq IDs: NR_028043, NR_028044, ENST00000381361, ENST00000381363, ENST00000445504
Description: Insulin-like growth factor 2 antisense
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 RT≤ Profilerô PCR ArrayInquire

Gene Symbol: IGF2 (Human)Other Aliases: C11orf43, IGF-II, PP9974
Refseq IDs: NM_000612, NM_001007139, NM_001127598, XM_005252899, XM_005252900, XM_005252901
Description: Insulin-like growth factor 2 (somatomedin A)
This gene encodes a member of the insulin family of polypeptide growth factors that is involved in development and growth. It is an imprinted gene and is expressed only from the paternally inherited allele. It is a candidate gene for eating disorders. There is a read-through, INS-IGF2, which aligns to this gene at the 3' region and to the upstream INS gene at the 5' region. Two alternatively spliced transcript variants encoding the same protein have been found for this gene.
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 RT≤ Profilerô PCR Array8 products

Gene Symbol: IGF1R (Human)Other Aliases: CD221, IGFIR, IGFR, JTK13
Refseq IDs: NM_000875, XM_005254896, XM_005254897, ENST00000268035, ENST00000557873, ENST00000557938, ENST00000558355, ENST00000558751, ENST00000558762, ENST00000558898, ENST00000558947, ENST00000559582, ENST00000559925, ENST00000560144, ENST00000560186, ENST00000560277, ENST00000560343, ENST00000560432, ENST00000560972, ENST00000561049
Description: Insulin-like growth factor 1 receptor
This receptor binds insulin-like growth factor with a high affinity. It has tyrosine kinase activity. The insulin-like growth factor I receptor plays a critical role in transformation events. Cleavage of the precursor generates alpha and beta subunits. It is highly overexpressed in most malignant tissues where it functions as an anti-apoptotic agent by enhancing cell survival.
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 RT≤ Profilerô PCR Array18 products

Gene Symbol: IGF1 (Human)Other Aliases: IGF-I, IGF1A, IGFI
Refseq IDs: NM_000618, NM_001111283, NM_001111284, NM_001111285, XM_005268835, XM_005268836, ENST00000307046, ENST00000337514, ENST00000392904, ENST00000392905, ENST00000424202, ENST00000456098, ENST00000481539
Description: Insulin-like growth factor 1 (somatomedin C)
The somatomedins, or insulin-like growth factors (IGFs), comprise a family of peptides that play important roles in mammalian growth and development. IGF1 mediates many of the growth-promoting effects of growth hormone (GH; MIM 139250). Early studies showed that growth hormone did not directly stimulate the incorporation of sulfate into cartilage, but rather acted through a serum factor, termed 'sulfation factor,' which later became known as 'somatomedin' (Daughaday et al., 1972). Three main somatomedins have been characterized: somatomedin C (IGF1), somatomedin A (IGF2; MIM 147470), and somatomedin B (MIM 193190) (Rotwein, 1986; Rosenfeld, 2003).[supplied by OMIM]
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 RT≤ Profilerô PCR Array33 products

Gene Symbol: FOXM1 (Human)Other Aliases: FKHL16, FOXM1B, HFH-11, HFH11, HNF-3, INS-1, MPHOSPH2, MPP-2, MPP2, PIG29, TGT3, TRIDENT
Refseq IDs: NM_021953, NM_202002, NM_202003, NM_001243088, NM_001243089, XM_005253676, XM_005253677, ENST00000342628, ENST00000359843, ENST00000361953, ENST00000366362, ENST00000535350, ENST00000536066, ENST00000537018, ENST00000538564, ENST00000545049
Description: Forkhead box M1
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 RT≤ Profilerô PCR Array3 products

Gene Symbol: AAAS (Human)Other Aliases: AAA, AAASb, ADRACALA, ADRACALIN, ALADIN
Refseq IDs: NM_015665, NM_001173466, ENST00000209873, ENST00000394384, ENST00000546393, ENST00000546562, ENST00000546572, ENST00000547238, ENST00000547520, ENST00000547757, ENST00000547761, ENST00000548258, ENST00000548880, ENST00000548931, ENST00000549450, ENST00000549821, ENST00000549983, ENST00000550033, ENST00000550286, ENST00000551724, ENST00000552161, ENST00000552876
Description: Achalasia, adrenocortical insufficiency, alacrimia
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 RT≤ Profilerô PCR ArrayInquire