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Browse Products By Gene


Search the entire catalog of SABiosciences products by gene name, key word, or RefSeq number. To learn more about all of these products, visit our Send an Email to Technical Support.

  1. Choose your species of interest first: Human, Mouse, Rat, Rhesus Macaque or Fruit Fly.
  2. Use Gene Symbols, key words, or RefSeq Accession Numbers for your gene of interest to find the catalog numbers for the corresponding products. To learn how to get RefSeq Accession Numbers, click here.
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  4. Click 'Submit'.
Species:
Gene Name, symbol, description:      RefSeq Number:   
All Product Lines
RT² Profiler™ PCR Array Pathway-Focused qRT-PCR Based Expression Profiling
RT² qPCR Primer Assay Gene-Specific Primers for qRT-PCR, Genome-Wide Availability
Cignal™ Pathway Reporter Assays Cell-Based Assays for Rapidly Analyzing Pathway Signaling Activity
miScript miRNA PCR Array miScript miRNA PCR Array
Multi-Analyte Profiler ELISArray Kits Analyze 12 Cytokines or Chemokines Simultaneously Using ELISA
Single Analyte ELISArray Kits High Performance ELISA with the Best Possible Antibodies
EpiTect Methyl II PCR Arrays Pathway-Focused PCR Based DNA Methylation Analysis
EpiTect Methyl II PCR Primer Assay PCR Assays for DNA Methylation Analysis, Genome-Wide Availability
SureSilencing™ shRNA Gene-Specific Plasmid-Based RNA Interference, Genome-Wide Availability
EpiTect ChIP qPCR Arrays Pathway-Focused qPCR Based Histone Modifications Analysis
        
Search Result: 31 gene(s) found matching 'TP53'
Gene Symbol: TP53 (Human)Other Aliases: FLJ92943, LFS1, P53, TRP53
Refseq IDs: NM_000546, NM_001126112, NM_001126113, NM_001126114, NM_001126115, NM_001126116, NM_001126117
Description: Tumor protein p53
Tumor protein p53, a nuclear protein, plays an essential role in the regulation of cell cycle, specifically in the transition from G0 to G1. It is found in very low levels in normal cells, however, in a variety of transformed cell lines, it is expressed in high amounts, and believed to contribute to transformation and malignancy. p53 is a DNA-binding protein containing DNA-binding, oligomerization and transcription activation domains. It is postulated to bind as a tetramer to a p53-binding site and activate expression of downstream genes that inhibit growth and/or invasion, and thus function as a tumor suppressor. Mutants of p53 that frequently occur in a number of different human cancers fail to bind the consensus DNA binding site, and hence cause the loss of tumor suppressor activity. Alterations of the TP53 gene occur not only as somatic mutations in human malignancies, but also as germline mutations in some cancer-prone families with Li-Fraumeni syndrome.
Products:
 RT² Profiler™ PCR Array38 products
Gene Symbol: GAMT (Human)Other Aliases: PIG2, TP53I2
Refseq IDs: NM_000156, NM_138924
Description: Guanidinoacetate N-methyltransferase
The protein encoded by this gene is a methyltransferase that converts guanidoacetate to creatine, using S-adenosylmethionine as the methyl donor. Defects in this gene have been implicated in neurologic syndromes and muscular hypotonia, probably due to creatine deficiency and accumulation of guanidinoacetate in the brain of affected individuals. Two transcript variants encoding different isoforms have been described for this gene.
Products:
 RT² Profiler™ PCR Array3 products
Gene Symbol: TP53AIP1 (Human)Other Aliases: P53AIP1
Refseq IDs: NM_022112, NM_001195194, NM_001195195
Description: Tumor protein p53 regulated apoptosis inducing protein 1
Products:
 RT² Profiler™ PCR Array1 products
Gene Symbol: TP53BP1 (Human)Other Aliases: 53BP1, FLJ41424, MGC138366, p202
Refseq IDs: NM_005657, NM_001141979, NM_001141980
Description: Tumor protein p53 binding protein 1
Products:
 RT² Profiler™ PCR Array3 products
Gene Symbol: TP53BP2 (Human)Other Aliases: 53BP2, ASPP2, BBP, P53BP2, PPP1R13A
Refseq IDs: NM_005426, NM_001031685
Description: Tumor protein p53 binding protein, 2
This gene encodes a member of the ASPP (apoptosis-stimulating protein of p53) family of p53 interacting proteins. The protein contains four ankyrin repeats and an SH3 domain involved in protein-protein interactions. It is localized to the perinuclear region of the cytoplasm, and regulates apoptosis and cell growth through interactions with other regulatory molecules including members of the p53 family. Multiple transcript variants encoding different isoforms have been found for this gene.
Products:
 RT² Profiler™ PCR Array4 products
Gene Symbol: TP53I11 (Human)Other Aliases: PIG11
Refseq IDs: NM_006034, NM_001076787
Description: Tumor protein p53 inducible protein 11
Products:
 RT² Profiler™ PCR ArrayInquire
Gene Symbol: TP53I13 (Human)Other Aliases: DSCP1
Refseq IDs: NM_138349
Description: Tumor protein p53 inducible protein 13
Products:
 RT² Profiler™ PCR ArrayInquire
Gene Symbol: TP53I3 (Human)Other Aliases: PIG3
Refseq IDs: NM_004881, NM_147184, NM_001206802
Description: Tumor protein p53 inducible protein 3
The protein encoded by this gene is similar to oxidoreductases, which are enzymes involved in cellular responses to oxidative stresses and irradiation. This gene is induced by the tumor suppressor p53 and is thought to be involved in p53-mediated cell death. It contains a p53 consensus binding site in its promoter region and a downstream pentanucleotide microsatellite sequence. P53 has been shown to transcriptionally activate this gene by interacting with the downstream pentanucleotide microsatellite sequence. The microsatellite is polymorphic, with a varying number of pentanucleotide repeats directly correlated with the extent of transcriptional activation by p53. It has been suggested that the microsatellite polymorphism may be associated with differential susceptibility to cancer. At least two transcript variants encoding the same protein have been found for this gene.
Products:
 RT² Profiler™ PCR Array1 products
Gene Symbol: TP53INP1 (Human)Other Aliases: DKFZp434M1317, FLJ22139, SIP, TP53DINP1, TP53INP1A, TP53INP1B, Teap, p53DINP1
Refseq IDs: NM_033285, NM_001135733
Description: Tumor protein p53 inducible nuclear protein 1
Products:
 RT² Profiler™ PCR Array3 products
Gene Symbol: TP53INP2 (Human)Other Aliases: C20orf110, DKFZp434B2411, DKFZp434O0827, DOR, FLJ21759, FLJ23500, PINH, dJ1181N3.1
Refseq IDs: NM_021202
Description: Tumor protein p53 inducible nuclear protein 2
Products:
 RT² Profiler™ PCR ArrayInquire
Gene Symbol: TP53RK (Human)Other Aliases: BUD32, C20orf64, Nori-2, Nori-2p, PRPK, dJ101A2
Refseq IDs: NM_033550
Description: TP53 regulating kinase
Products:
 RT² Profiler™ PCR ArrayInquire
Gene Symbol: TP53TG1 (Human)Other Aliases: NCRNA00096, P53TG1, P53TG1-D, TP53AP1
Refseq IDs: NR_015381
Description: TP53 target 1 (non-protein coding)
Products:
 RT² Profiler™ PCR ArrayInquire
Gene Symbol: TP53TG3 (Human)Other Aliases: P53TG3, TP53TG3A, TP53TG3B, TP53TG3C, TP53TG3D
Refseq IDs: NM_016212
Description: TP53 target 3
Products:
 RT² Profiler™ PCR ArrayInquire
Gene Symbol: TP53TG3B (Human)Other Aliases: MGC119888, TP53TG3, TP53TG3A, TP53TG3C, TP53TG3D
Refseq IDs: NM_001099687, NM_001205265
Description: TP53 target 3B
Products:
 RT² Profiler™ PCR ArrayInquire
Gene Symbol: TP53TG5 (Human)Other Aliases: C20orf10, CLG01
Refseq IDs: NM_014477
Description: TP53 target 5
Products:
 RT² Profiler™ PCR ArrayInquire
Gene Symbol: WRAP53 (Human)Other Aliases: FLJ10385, TCAB1, WDR79
Refseq IDs: NM_018081, NM_001143990, NM_001143991, NM_001143992
Description: WD repeat containing, antisense to TP53
Products:
 RT² Profiler™ PCR Array1 products
Gene Symbol: TRIAP1 (Human)Other Aliases: P53CSV, WF-1
Refseq IDs: NM_016399
Description: TP53 regulated inhibitor of apoptosis 1
Products:
 RT² Profiler™ PCR Array1 products
Gene Symbol: TPRKB (Human)Other Aliases:
Refseq IDs: NM_016058
Description: TP53RK binding protein
Products:
 RT² Profiler™ PCR ArrayInquire
Gene Symbol: TP63 (Human)Other Aliases: AIS, B(p51A), B(p51B), EEC3, KET, LMS, NBP, OFC8, RHS, SHFM4, TP53CP, TP53L, TP73L, p40, p51, p53CP, p63, p73H, p73L
Refseq IDs: NM_003722, NM_001114978, NM_001114979, NM_001114980, NM_001114981, NM_001114982
Description: Tumor protein p63
Products:
 RT² Profiler™ PCR Array3 products
Gene Symbol: TOPORS (Human)Other Aliases: LUN, P53BP3, RP31, TP53BPL
Refseq IDs: NM_005802, NM_001195622
Description: Topoisomerase I binding, arginine/serine-rich, E3 ubiquitin protein ligase
Products:
 RT² Profiler™ PCR Array2 products
Gene Symbol: SAA1 (Human)Other Aliases: MGC111216, PIG4, SAA, SAA2, TP53I4
Refseq IDs: NM_000331, NM_199161, NM_001178006
Description: Serum amyloid A1
Products:
 RT² Profiler™ PCR Array1 products
Gene Symbol: RRM2B (Human)Other Aliases: DKFZp686M05248, MGC102856, MGC42116, MTDPS8A, MTDPS8B, P53R2
Refseq IDs: NM_015713, NM_001172477, NM_001172478
Description: Ribonucleotide reductase M2 B (TP53 inducible)
Products:
 RT² Profiler™ PCR ArrayInquire
Gene Symbol: RPRM (Human)Other Aliases: FLJ90327, REPRIMO
Refseq IDs: NM_019845
Description: Reprimo, TP53 dependent G2 arrest mediator candidate
Products:
 RT² Profiler™ PCR Array1 products
Gene Symbol: PTGES (Human)Other Aliases: MGC10317, MGST-IV, MGST1-L1, MGST1L1, MPGES, PGES, PIG12, PP102, PP1294, TP53I12, mPGES-1
Refseq IDs: NM_004878
Description: Prostaglandin E synthase
The protein encoded by this gene is a glutathione-dependent prostaglandin E synthase. The expression of this gene has been shown to be induced by proinflammatory cytokine interleukin 1 beta (IL1B). Its expression can also be induced by tumor suppressor protein TP53, and may be involved in TP53 induced apoptosis. Knockout studies in mice suggest that this gene may contribute to the pathogenesis of collagen-induced arthritis and mediate acute pain during inflammatory responses.
Products:
 RT² Profiler™ PCR Array2 products
Gene Symbol: PRODH (Human)Other Aliases: FLJ33744, HSPOX2, MGC148078, MGC148079, PIG6, POX, PRODH1, PRODH2, SCZD4, TP53I6
Refseq IDs: NM_016335, NM_001195226
Description: Proline dehydrogenase (oxidase) 1
The protein encoded by this gene is a mitochondrial proline dehydrogenase which catalyzes the first step in proline catabolism. Deletion of this gene has been associated with type I hyperprolinemia. The gene is located on chromosome 22q11.21, a region which has also been associated with the contiguous gene deletion syndromes DiGeorge syndrome and CATCH22 syndrome.
Products:
 RT² Profiler™ PCR Array3 products
Gene Symbol: PERP (Human)Other Aliases: KCP1, KRTCAP1, PIGPC1, RP3-496H19.1, THW, dJ496H19.1
Refseq IDs: NM_022121
Description: PERP, TP53 apoptosis effector
Products:
 RT² Profiler™ PCR Array2 products
Gene Symbol: MAD1L1 (Human)Other Aliases: MAD1, PIG9, TP53I9, TXBP181
Refseq IDs: NM_003550, NM_001013836, NM_001013837
Description: MAD1 mitotic arrest deficient-like 1 (yeast)
MAD1L1 is a component of the mitotic spindle-assembly checkpoint that prevents the onset of anaphase until all chromosome are properly aligned at the metaphase plate. MAD1L1 functions as a homodimer and interacts with MAD2L1. MAD1L1 may play a role in cell cycle control and tumor suppression. Three transcript variants encoding the same protein have been found for this gene.
Products:
 RT² Profiler™ PCR ArrayInquire
Gene Symbol: LITAF (Human)Other Aliases: FLJ38636, MGC116698, MGC116700, MGC116701, MGC125274, MGC125275, MGC125276, PIG7, SIMPLE, TP53I7
Refseq IDs: NM_004862, NM_001136472, NM_001136473, NR_024320
Description: Lipopolysaccharide-induced TNF factor
Products:
 RT² Profiler™ PCR ArrayInquire
Gene Symbol: ENC1 (Human)Other Aliases: CCL28, ENC-1, FLJ39259, KLHL35, KLHL37, NRPB, PIG10, TP53I10
Refseq IDs: NM_003633
Description: Ectodermal-neural cortex 1 (with BTB-like domain)
DNA damage and/or hyperproliferative signals activate wildtype p53 tumor suppressor protein (TP53; MIM 191170), inducing cell cycle arrest or apoptosis. Mutations that inactivate p53 occur in 50% of all tumors. Polyak et al. (1997) used serial analysis of gene expression (SAGE) to evaluate cellular mRNA levels in a colorectal cancer cell line transfected with p53. Of 7,202 transcripts identified, only 14 were expressed at levels more than 10-fold higher in p53-expressing cells than in control cells. Polyak et al. (1997) termed these genes 'p53-induced genes,' or PIGs, several of which were predicted to encode redox-controlling proteins. They noted that reactive oxygen species (ROS) are potent inducers of apoptosis. Flow cytometric analysis showed that p53 expression induces ROS production, which increases as apoptosis progresses under some conditions. The authors stated that the PIG10 gene, also called ENC1, encodes an actin-binding protein.[supplied by OMIM]
Products:
 RT² Profiler™ PCR Array1 products
Gene Symbol: EI24 (Human)Other Aliases: EPG4, PIG8, TP53I8
Refseq IDs: NM_004879, NM_001007277
Description: Etoposide induced 2.4 mRNA
This gene has higher expression in p53-expressing cells than in control cells and is an immediate-early induction target of p53-mediated apoptosis. The protein encoded by this gene contains six putative transmembrane domains and may suppress cell growth by inducing apoptotic cell death through the caspase 9 and mitochondrial pathways. This gene is located on human chromosome 11q24, a region frequently altered in cancers. Alternative splicing results in two transcript variants encoding different isoforms.
Products:
 RT² Profiler™ PCR Array2 products
Gene Symbol: ANO9 (Human)Other Aliases: PIG5, TMEM16J, TP53I5
Refseq IDs: NM_001012302
Description: Anoctamin 9
Products:
 RT² Profiler™ PCR ArrayInquire
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