Androgen Receptor and Associated Proteins: AR, NR1I3, RNF14, SHBG, SRD5A2, TGFB1I1. Apoptosis: Induction of Apoptosis: BAK1, BAX, CASP3, CDKN1A, DAPK1, INHA, MAPK1, NOX5, PRKCA, PRKCE, TIMP3, TNFSF10, TP53. Caspases: CASP1, CASP3, CASP7. Anti-apoptosis: AKT1, BCL2, BCL2L1, IGF1R, IL1A, IL2, NFKB1, PRKCZ, TGFB1, TNF. Other Apoptosis Genes: AGTR2, BRCA1, CLU, E2F1, IGFBP3, IL1B, IL24, NFKBIA, PAWR, VEGF. Cell Cycle: Cell Cycle Checkpoint: BRCA1, CDKN2A, RB1, TP53. Cell Ccle Arrest: CDKN1A, CDKN1B, CDKN1C, CDKN2A, CDKN2B, CDKN2C, CDKN3, INHA, MAPK12, MYC, RASSF1, TP53. Negative Regulation of the Cell Cycle: APC, BAX, BRCA1, CDKN1C, CDKN2A, CDKN2B, EGFR, ESR1, FHIT, INHA, KLK10, MAPK12, MTSS1, PTEN, RASSF1, RB1, TP53. Other Regulators of the Cell Cycle: BCL2, CCND1, CDK2, CDK3, CDK4, CDK5, CDK6, CDK7, CDK8, CDK9, E2F1, FGF1, FGF10, FGF2, FGF3, FGF4, FGF5, FGF6, FGF7, FGF8, FGF9, HK2, HRAS, IGF1R, IGF2, IL1A, IL1B, MAPK1, MAPK13, MAPK3, MAPK4, MAPK6, MAPK7, PCNA, PRKCA, TGFA, TGFB1, TGFB2, TGFB3, VEGF. Cell Growth and Proliferation: Cytokines: BMP6, IL12A, IL1A, IL1B, IL2, IL24, INHA, TNF, TNFSF10 Growth Factors: BMP6, EGF, FGF1, FGF10, FGF11, FGF12, FGF13, FGF14, FGF16, FGF17, FGF18, FGF19, FGF2, FGF20, FGF21, FGF22, FGF23, FGF3, FGF4, FGF5, FGF6, FGF7, FGF8, FGF9, GRP, IGF1, IGF2, IL12A, IL1A, IL1B, IL2, INHA, TGFA, TGFB1, TGFB2, TGFB3, VEGF Positive Regulation of Cell Proliferation: CDK2, EGF, FGF10, FGF18, FGF2, FGF4, FGF7, IGF1, IGF1R, IL2, VEGF Negative Regulation of Cell Proliferation: BCL2, CD164, CDKN1A, CDKN1B, CDKN1C, CDKN2A, CDKN2B, CDKN2C, CDKN3, GNRH1, IGFBP6, IL1A, IL1B, ODZ1, PAWR, PLG, TGFB1I1 Other Regulators of Cell Growth and Proliferation: AR, BRCA1, CDK3, CDK4, CDK5, CDK6, CDK7, CDK9, E2F1, EGFR, ENO1, ERBB2, ESR1, ESR2, IGFBP3, IGFBP6, IL2, INSL4, MYC, NOX5, NR6A1, PAP, PCNA, PRKCQ, PRKD1, PRL, TP53 Cell Differentiation: FGF22, FGF23, FGF9, IGFBP3, IL2, INHA, KLK6, TP53. Hormones and Related Genes: Hormones: CHGB, GNRH1, IGF1, IGF2, INHA, INSL3, INSL4, PRL. Hormone Regulators: KLK6, SHBG. Thyroid Hormone Receptors: NR1D1, NR1H3, NR1I3, NR2F6, NR4A3. Other Steroid Hormone Receptors: AR, ESR1, ESR2, NR0B1, NR0B2, NR1D2, NR1H2, NR1H4, NR1I2, NR2C1, NR2C2, NR2E1, NR2E3, NR2F1, NR2F2, NR3C1, NR3C2, NR4A1, NR4A2, NR5A1, NR5A2, NR6A1, PGR, RARB. Angiogenesis Factors: FGF1, FGF2, FGF6, KLK3, KRT1, VEGF. Extracellular Matrix (ECM): APOC1, BRCA1, CHGA, CHGB, CLU, COL1A1, COL6A1, EGF, ERBB2, ERK8, FGF1, FGF10, FGF11, FGF13, FGF14, FGF16, FGF17, FGF18, FGF2, FGF20, FGF21, FGF22, FGF23, FGF3, FGF4, FGF5, FGF6, FGF7, FGF8, FGF9, GNRH1, IGF1, IGF2, IGFBP3, IGFBP6, IL12A, IL1A, IL1B, IL2, IL24, INHA, INSL3, INSL4, KLK10, KLK12, KLK13, KLK14, KLK15, KLK3, KLK4, KLK5, KLK6, KLK9, MMP2, MMP9, MSMB, NTN4, ODZ1, PAP, PLAU, PRL, PSAP, SERPINA3, SHBG, TGFA, TIMP3, VEGF. Cell Adhesion: Cell- Cell Adhesion: CD44, CDH1, CDH10, CDH19, CDH20, CDH7, CDH9. Homophilic Cell Adhesion: CDH1, CDH10, CDH13, CDH18, CDH19, CDH20, CDH7, CDH8, CDH9, ROBO2. Cell-Matrix Adhesion: CD44, ILK, ITGA1. Other Cell Adhesion Regulators: APC, CD164, COL6A1, MTSS1, PAP, TGFB1I1, TNF. Proteases and Inhibitors: Kallikreins: KLK1, KLK10, KLK11, KLK12, KLK13, KLK14, KLK15, KLK2, KLK3, KLK4, KLK5, KLK6, KLK7, KLK8, KLK9. Metallopeptidases: FOLH1, MMP2, MMP9. Other proteases: CASP1, CASP3, CASP7, PLAU, PLG. Protease inhibitors: SERPINA3, TIMP3. Protein Kinases and Inhibitors: Cyclin-dependent Protein Kinases: CDK2, CDK3, CDK4, CDK5, CDK7, CDK9, CDK Inhibitors, AGTR2, CDKN1A, CDKN1B, CDKN1C, CDKN2A, CDKN2B, CDKN2C. JUN Kinases: MAPK10, MAPK8, MAPK9. MAP Kinases: ERK8, MAPK1, MAPK10, MAPK11, MAPK12, MAPK13, MAPK14, MAPK3, MAPK4, MAPK6, MAPK7, MAPK8, MAPK9. MAP Kinase Kinases: MAPK10, MAPK14. Protein Kinase C Members: PRKCA, PRKCB1, PRKCE, PRKCG, PRKCH, PRKD3. Janus Kinases: INSL3, TYK2. Other Protein Kinases: AKT1, CDK6, CDK8, DAPK1, EGFR, ERBB2, HK2, HK3, IGF1R, ILK, MAP2K4, MAP3K1, PRKCD, PRKCI, PRKCQ, PRKCZ, PRKD1, PRKD2, RNASEL, SRC, TGFA. Transcription Factors and Regulators: Nuclear Receptors: ESR1, ESR2, NR0B1, NR0B2, NR1D1, NR1D2, NR1H2, NR1H3, NR1H4, NR1I2, NR1I3, NR2C1, NR2C2, NR2E1, NR2E3, NR2F1, NR2F2, NR2F6, NR3C1, NR3C2, NR4A1, NR4A2, NR4A3, NR5A1, NR5A2, NR6A1, PGR, RARB. Other Transcription Factors and Regulators: AR, BRCA1, CDK7, CDK8, CDK9, E2F1, EGR3, ELL, ENO1, EZH1, EZH2, FGF10, HIF1A, JUN, MYC, NCOA4, NFKB1, NFKBIA, NKX3-1, PAWR, PIAS1, RB1, RNF14, SOX2, TGFB1I1, TNF, TP53, TRPS1. Genes Involved in Stress Response: Antibacterial Humoral Response: IL12A, IL1B, MAPK11, MAPK14, NFKB1, NR4A2. Inflammatory Response: IL1A, IL1B, NFKB1, NR3C1, PAP, SERPINA3, TNF. Other Stress Response Genes: AKT1, BRCA1, CD164, FGF10, FGF16, FGF7, HIF1A, IL2, IL24, INHA, KLK6, KRT1, MAPK1, MAPK11, MAPK13, MAPK14, MAPK8, MAPK9, NFKB1, NFKBIA, ODZ1, TNF, TNFSF10, TP53, VEGF. Other Prostate Cancer Markers: AGR2, AIG1, AKAP1, AKAP2, CANT1, CAV1, CDH12, CLDN3, CLN3, CYB5, CYC1, DAB2IP, DES, DNCL1, ELAC2, ENO2, ENO3, FASN, FLJ12584, FLJ25530, GAGEB1, GAGEC1, GGT1, GSTP1, HIP1, HUMCYT2A, IL29, K6HF, KAI1, KRT2A, MIB1, PART1, PATE, PCA3, PIAS2, PIK3CG, PPID, PR1, PSCA, SLC2A2, SLC33A1, SLC43A1, STEAP, STEAP2, TPM1, TPM2, TRPC6. |
