RT² Predictor PCR Arrays

The RT² Predictor PCR arrays are designed for determining levels of pathway activity or cellular toxicity using real time PCR and biomarker signature genes in an objective, accurate, reproducible, and medium throughput manner. Biomarker signature genes were experimentally derived specifically for each PCR Array. Each 96-well or 384-well plate PCR Array includes SYBR Green-optimized primer assays for multiple sets of pathway specific biomarker signature genes enabling determination of pathway activity regulation in 4 or 16 samples, respectively, simultaneously with a single PCR run.

Using a simple real time PCR, the RT2 Predictor PCR Array can easily and rapidly:

• Monitor pathway activity  
• Study pharmacodynamics or toxicodynamics
• Analyze drug response sensitivity 

Why RT² Predictor PCR Arrays?

• Pathway activity score: Each PCR Array has specific companion algorithm that converts gene expression of biomarker signature into signaling pathways or cellular tocixity level score providing an objective means of determining pathway activity regulation.
• Time and cost saving: Less handling time and small amount of sample required  compared to protein or reporter analysis

Learn about how RT² Predictor Arrays work

RT² Predictor PCR Arrays:

Determine levels of pathway activity or cellular toxicity with our laboratory verified arrays. View the entire list of Arrays.

• Determine levels of pathway activity  - Determine how the activity of a specific signaling pathway changes in your experimental vs. control samples
• Human WNT Signaling Pathway Activity
• Human IL6/STAT3 Signaling Pathway Activity
• Human TGFb Signaling Pathway Activity
• Human Notch Signaling Pathway Activity
• Human NFkB Signaling Pathway Activity
• Determine levels of cellular toxicity - Determine if a specific treatment induces cellular toxicity in your experimental vs. control samples
• Human Oxidative Stress Toxicity
• Human Hypoxia Signaling Pathway Activity
• Human Unfolded Protein Response Toxicity
• Human Mitochondrial Energy Metabolism Toxicity
• RT² SYBR Green Mastermix - Guaranteed qPCR master mix for RT² Predictor PCR Arrays

Accessories for RT² Predictor PCR Arrays

• RT² First Strand Kits
  Sensitive qRT-PCR with RNA Quality Control and NO Genomic DNA Worries
• RT² qPCR Master Mixes
  Instrument-Specific Formulations, Ready-to-Use
• RNeasy Mini Kit
  For purification of up to 100 µg total RNA from cells and tissues
• RNase-Free DNase Set
  For DNase digestion during RNA purification
• RT² PCR Array Loading Reservoir
  Optimized reservoir for sample loading of PCR Arrays.
• RT² RNA QC PCR Array
  Tests for RNA Quality and Inhibitors of RT-PCR Analyses

 Supporting Information

• User Manual / Handbook
• Data Analysis
• Webinars
• Powerpoint Slides