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Online Seminars

SABiosciences is pleased to provide free, on-line educational resources covering relevant tools and techniques for gene and protein expression analysis, and cell-based gene function analysis. We offer live webinars, prerecorded and PDF formatted presentations.

See the instructions for the Web Seminars

May 2015
Monday
Tuesday
Wednesday
Thursday
Friday

1

4

Molecular Mechanisms of Neurodegeneration

5

Critical factors for successful multiplex endpoint PCR

QPCR Introduction

6

Exosomes in liquid biopsy

7

NGS: an introduction to technology and applications

8

Host–pathogen interactions

11

Circulating Biomarkers for Alzheimer’s Disease

12

Critical factors for successful multiplex qPCR

Coding & noncoding RNA analysis using qPCR

13

Maximize quantity and purity of exosomal RNA

14

Addressing the challenges of NGS workflow

15

Microbiome: From identification to characterization

18

Non-Coding RNAs in Neurodegenerative Disorders

19

PCR Array Data Analysis Tutorial

20

Biomarker discovery in biofluids

21

Target NGS for cancer research

22

Research tools for the innate immune system

25

26

Service for biomarker research

27

Meeting the challenges of biomarker research

Integrated sample isolation solutions

28

Advance data Analysis with IVA and CLC Bio Cancer Workbench

29

Toll-like Receptors in Inflammation

Current Seminar Titles Available:

Focus Title
1.  PCR ArrayPCR Array Data Analysis Tutorial
2.  QPCR IntroductionIntroduction to Real Time PCR (Q-PCR/qPCR/qrt-PCR)
3.  PCR Arrays in ImmunologyExploring the first line of defense: research tools for the innate immune system
4.  Inflammation and TLRToll-like Receptors in Inflammation
5.  Next-generation sequencingNext-generation sequencing, an introduction to technology and applications
6.  Microbial PCR ArraysMicrobiome: From identification to characterization
7.  Host–Pathogen InteractionsHost–Pathogen Interactions: Molecular Basis and Host Defense Mechanisms
8.  Next-generation sequencingNext-Generation Sequencing — Targeted Enrichment Technology in Cancer Research
9.  Next-generation sequencingAdvancing NGS Data Analysis and Interpretation: CLC Cancer Research Workbench and Ingenuity Variant Analysis
10.  Liquid BiopsiesExosomes as Liquid Biopsy: From Molecular Phenotype to Functional Mechanisms
11.  Liquid BiopsiesExosome Research – Maximize Quantity and Purity of Exosomal RNA
12.  miRNA BiomarkerBiomarker Discovery in Biofluids: from Sample to Biomarker
13.  miRNA BiomarkerMeeting the Challenges of Biomarker Research: miRNA Function, Profiling and Data Analysis
14.  Next-generation sequencingAddressing the challenges of NGS workflow: sample preparation, quality control and automation
15.  Service CoreAccelerate your discovery with QIAGEN service solutions for biomarker research
16.  NeurodegenerationCirculating Biomarkers for Alzheimer’s Disease
17.  NeurodegenerationThe Central Roles of Non-Coding RNAs in Neurodegenerative Disorders
18.  Sample IsolationIntegrated sample isolation for cancer, immunology, and microbiome studies
19.  Multiplex PCRCritical Factors for Successful Multiplex Real-Time PCR
20.  PCR ArraysAdvanced Real-Time PCR Array Technology – Coding & Noncoding RNA Expression Analysis

PCR Array Data Analysis Tutorial

With a live demonstration using actual PCR array data, learn how easy it is to use our data analysis Web portal to calculate fold-differences in gene expression from your raw real-time PCR threshold cycles.

Duration: 45 minutes followed by Q&A session.

Schedule:

Tuesday, May 19, 2015 at 1:00 PM Eastern    Status: Available Reserve

Introduction to Real Time PCR (Q-PCR/qPCR/qrt-PCR)

Real-time polymerase chain reaction (qPCR) is the most sensitive and reliable method for the detection and quantification of nucleic acids. This 45-minute webinar introduces the concepts of real-time PCR and how to conduct a real-time PCR assay. The topics that will be covered include an overview of real-time PCR chemistries, protocols, quantification methods, real-time PCR applications, and factors for success. This webinar is for both beginners that are new to real-time PCR as well as experienced users.

Duration: 45 minutes followed by Q&A session.

Schedule:

Tuesday, May 5, 2015 at 1:00 PM Eastern    Status: Available Reserve

Exploring the first line of defense: research tools for the innate immune system

The innate immune system executes crucial and unique functions for host defense against infection. This webinar provides an overview of the most important cellular and molecular players of innate immunity and discusses their functions in a variety of disease states. We also introduce research technologies for exploring innate immune activity in your system through profiling of gene expression and cytokines, signal transduction pathway analysis and more, all in the context.

Duration: 45 minutes followed by Q&A session.

Schedule:

Friday, May 22, 2015 at 1:00 PM Eastern    Status: Available Reserve

Toll-like Receptors in Inflammation

"Toll-like receptors (TLRs) have been implicated in both innate and adaptive immunity-induced inflammation, thereby playing critical roles in providing the host with short- and long-term protection against infections.. This webinar will provide an overview of the roles that TLRs play in the regulation of Inflammation and solutions for studying these roles. An overview of TLR-mediated inflammation, the key signaling players involved in TLR-mediated inflammation, and the contribution of TLR-mediated inflammation to various physiological processes will be presented. Please come and learn about the state-of-the-art research tools for analyzing TLR-mediated inflammation and its regulation. "

Duration: 45 minutes followed by Q&A session.

Schedule:

Friday, May 29, 2015 at 1:00 PM Eastern    Status: Available Reserve

Next-generation sequencing, an introduction to technology and applications

Next-generation sequencing (NGS) technology has revolutionized the study of the genomes, transcriptomes and epigenomes of any species. NGS employs massively parallel sequencing to poduce millions of sequences at once and delivering fast, inexpensive, and accurate genome information. This webinar will provide a technical overview of DNA/RNA preprocessing, template preparation, sequencing, and data analysis. It will also cover the applications for NGS technologies, including guidelines for how to select the technology that will best address your biological question of interest.

Duration: 45 minutes followed by Q&A session.

Schedule:

Thursday, May 7, 2015 at 1:00 PM Eastern    Status: Available Reserve

Microbiome: From identification to characterization

Duration: 45 minutes followed by Q&A session.

Schedule:

Friday, May 15, 2015 at 1:00 PM Eastern    Status: Available Reserve

Host–Pathogen Interactions: Molecular Basis and Host Defense Mechanisms

Host–pathogen interactions are strikingly complex during infection. This webinar provides an overview of the molecular basis of these intricate interactions; the impact of microbiota on innate and adaptive immunity, metabolism, and insulin resistance; and host defense mechanisms, including newly reported inflammasome-mediated responses and miRNA-mediated responses. Various research tools will be introduced to simplify and streamline each step of studying the host response, enabling analysis of gene expression and regulation, epigenetic modification, genotyping, and signal transduction pathway activation.

Duration: 45 minutes followed by Q&A session.

Schedule:

Friday, May 8, 2015 at 1:00 PM Eastern    Status: Available Reserve

Next-Generation Sequencing — Targeted Enrichment Technology in Cancer Research

Genetic variance analysis plays a critical role cancer diagnosis, prognosis and treatment of cancer. Low sample volume and poor DNA quality are nagging issues with cancer samples making the results unreliable and expensive. This webinar discusses the most biologically efficient, cost-effective method for successful NGS. The GeneRead DNA QuantiMIZE Kits enable determination of the optimum conditions for targeted enrichment of DNA isolated from biological samples, while the GeneRead DNAseq Panels V2 allow you to quickly and reliably deep sequence your genes of interest. Applications in translational and clinical research will be highlighted.

Duration: 45 minutes followed by Q&A session.

Schedule:

Thursday, May 21, 2015 at 1:00 PM Eastern    Status: Available Reserve

Advancing NGS Data Analysis and Interpretation: CLC Cancer Research Workbench and Ingenuity Variant Analysis

Deep-sequencing technologies are enabling critical insights into all aspects of cancer genomics. This webinar will discuss two comprehensive informatics solutions — the CLC Cancer Research Workbench and Ingenuity Knowledge Base Variant Analysis platforms. These NGS analysis platforms provide a user-friendly and customizable solution, enabling you to easily narrow down your focus to causal variants and detect and annotate low-frequency somatic variants. We will show the intuitive user interface of CLC Cancer Research Workbench and demonstrate how the rich biological content from Ingenuity Knowledge Base helps you rapidly identify critical variants in your samples.

Duration: 45 minutes followed by Q&A session.

Schedule:

Thursday, May 28, 2015 at 1:00 PM Eastern    Status: Available Reserve

Exosomes as Liquid Biopsy: From Molecular Phenotype to Functional Mechanisms

Exosomes are small vesicles secreted by all types of cells and found abundantly in body fluids such as blood, saliva and urine. These extracellular vesicles (EVs) carry a variety of functional components including DNA, miRNA, non-coding RNA, proteins and lipids, and function as intercellular communication vehicles by transferring these signaling molecules between specific cells. This webinar will discuss the current understanding of their biogenesis, molecular phenotype and functional mechanisms, with a focus on their potential for use in liquid biopsy.

Duration: 45 minutes followed by Q&A session.

Schedule:

Wednesday, May 6, 2015 at 9:30 AM Eastern    Status: Available Reserve

Exosome Research – Maximize Quantity and Purity of Exosomal RNA

Recent years have seen an increased interest in the significance of RNA and other molecules carried by exosomes and other extracellular vesicles (EVs). Specifically, these vesicles may be the key to identifying circulating biomarkers. The major limitation of this strategy is the ability to isolate these exosomes in a standardized manner. Until now, methods for purifying exosomes for RNA isolation have been time-consuming and inconsistent. QIAGEN has developed solutions to help isolate and enrich exosomes and other extracellular vesicles, to allow the detection of low-abundance RNAs that are in circulation. The seminar will describe new solutions for sample preparation and discuss how to maximize quantity and purity of low-abundance fragments.

Duration: 45 minutes followed by Q&A session.

Schedule:

Wednesday, May 13, 2015 at 9:30 AM Eastern    Status: Available Reserve

Biomarker Discovery in Biofluids: from Sample to Biomarker

Developing novel non-invasive biomarkers holds great promise in improving detection and prognostic evaluation of cancer. Circulating microRNAs are promising candidates, as they reflect the key characteristics of cancer biomarkers and are highly stable in biofluids. This webinar presents an integrated system for circulating biomarker discovery from sample to insight. Advanced techniques for exosomal miRNA isolation and miRNA detection will be discussed.

Duration: 45 minutes followed by Q&A session.

Schedule:

Wednesday, May 20, 2015 at 9:30 AM Eastern    Status: Available Reserve

Meeting the Challenges of Biomarker Research: miRNA Function, Profiling and Data Analysis

Recent studies have shown strong evidence that aberration in microRNA regulation is associated with many disease processes including cancer and neurodegenerative diseases, indicating the huge potential of miRNAs as diagnostic and prognostic biomarkers. This webinar addresses the current challenges associated with miRNA quantification by real-time PCR, and the latest strategies for miRNA quantification and profiling. The critical parameters of profiling miRNA gene expression and a free web-based miRNA data analysis tool will also be presented.

Duration: 45 minutes followed by Q&A session.

Schedule:

Wednesday, May 27, 2015 at 9:30 AM Eastern    Status: Available Reserve

Addressing the challenges of NGS workflow: sample preparation, quality control and automation

The rapid technological advances in NGS have revolutionized the field of genomics, and broaden the applications from basic research, translational to clinical research. However, there exist enormous challenges in terms of sample preparation, sample quality control, and library preparation, which affect sequencing quality. This webinar will focus on these challenges and discuss various solutions to tackle these challenges and maximize your NGS workflow.

Duration: 45 minutes followed by Q&A session.

Schedule:

Thursday, May 14, 2015 at 1:00 PM Eastern    Status: Available Reserve

Accelerate your discovery with QIAGEN service solutions for biomarker research

Development of preclinical biomarkers can have several pitfalls, often requiring a large investment in instruments to process samples, time to develop assays, and specialties in data analysis and biomarker algorithm design. QIAGEN’s life sciences service core can provide researchers with the tools, knowledge and specialties to help develop the next generation of biomarkers for cancer, toxicology and inflammation research. This seminar will highlight QIAGEN’s service capabilities in sample isolation, microarray and NGS-sequencing, qPCR panel, and custom assay development and bioinformatics as we look at the identification of potential biomarkers and gene signatures. We will discuss the applications of QIAGEN Service Core in microRNA discovery for toxicology markers in serum and plasma and in identification of RNA signatures for tumor stratification. Join us and learn how you can accelerate your research with QIAGEN service solutions.

Duration: 45 minutes followed by Q&A session.

Schedule:

Tuesday, May 26, 2015 at 1:00 PM Eastern    Status: Available Reserve

Circulating Biomarkers for Alzheimer’s Disease

Alzheimer's disease (AD) is a complex neurodegenerative disorder. Circulating miRNAs hold great promise in the discovery of non-invasive and novel biomarkers for AD diagnosis and prognosis. This webinar will review the role of miRNAs in AD and discuss current progress in biomarker discovery. We will present various tools for pathway-focused and genomewide miRNA expression profiling, miRNA functional studies and target identification.

Duration: 45 minutes followed by Q&A session.

Schedule:

Monday, May 11, 2015 at 9:30 AM Eastern    Status: Available Reserve

The Central Roles of Non-Coding RNAs in Neurodegenerative Disorders

Non-coding RNAs (ncRNAs), especially microRNAs (miRNAs) and long non-coding RNAs (lncRNAs) have shown aberrant expression profiles in neurodegenerative disorders. This webinar will review the roles of lncRNAs and their mechanisms of action in the regulation of neurodegeneration. Their potential as circulating biomarkers will be discussed. Novel solutions to isolate RNAs from blood and cerebral spinal fluid (CSF) will be discussed and a new qPCR-based lncRNA platform for lncRNA detection and profiling will also be introduced.

Duration: 45 minutes followed by Q&A session.

Schedule:

Monday, May 18, 2015 at 9:30 AM Eastern    Status: Available Reserve

Integrated sample isolation for cancer, immunology, and microbiome studies

The central dogma of molecular biology, genes to messenger to protein, guides a principle of molecular biology research: that to fully understand gene expression, one should look at each level of the process. However, limitations in sample amount and time can make isolating DNA, RNA, and protein a tricky prospect. In this webinar, we will discuss how you can simultaneously extract DNA and total RNA, or DNA, RNA, and protein, from the same sample. Case studies using this technology in cancer, immunology, and microbiology studies will also be discussed. Come join us to learn how you can simplify your sample preparation and enhance your molecular biology studies!

Duration: 45 minutes followed by Q&A session.

Schedule:

Wednesday, May 27, 2015 at 1:00 PM Eastern    Status: Available Reserve

Critical Factors for Successful Multiplex Real-Time PCR

Multiplex real-time PCR is a powerful tool for gene expression analysis, viral load monitoring, genotyping, and many other applications. The ability to amplify and detect several genomic DNA, cDNA, or RNA targets in the same reaction offers many benefits: • Conservation of precious samples – more quantification data per sample • Increased throughput – more targets analyzed per run on a cycler • Reliable results – no well-to-well variability due to co-amplification of internal control • Reduced costs – save time and reagents The QuantiFast Multiplex PCR and RT-PCR kits are optimized for reliable amplification of many different templates despite a high variability in abundance. Thus they enable successful amplification of multiple targets on the first attempt without optimization. This webinar explains the principles of the QIAGEN multiplex technologies and shows data demonstrating the exceptional multiplex real-time PCR performance of the QuantiFast Multiplex kits.

Duration: 45 minutes followed by Q&A session.

Schedule:

Tuesday, May 12, 2015 at 9:30 AM Eastern    Status: Available Reserve

Advanced Real-Time PCR Array Technology – Coding & Noncoding RNA Expression Analysis

This webinar presents a simple and accurate real-time PCR system for relevant biological pathway- & disease-focused mRNA and long non-coding RNA (lncRNA) expression profiling. Learn about the stringent performance built into the technology to insure its sensitivity, specificity, reproducibility, and reliability. Application examples will be presented.

Duration: 45 minutes followed by Q&A session.

Schedule:

Tuesday, May 12, 2015 at 1:00 PM Eastern    Status: Available Reserve

Note: Viewers will be asked to register before viewing the previously recorded webinars.