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Online Seminars

SABiosciences is pleased to provide free, on-line educational resources covering relevant tools and techniques for gene and protein expression analysis, and cell-based gene function analysis. We offer live webinars, prerecorded and PDF formatted presentations.

See the instructions for the Web Seminars

December 2014
Monday
Tuesday
Wednesday
Thursday
Friday

1

Inflammation, ROS and aging

Host–pathogen interactions

2

QPCR Introduction

Tumor heterogeneity

3

NGS: an introduction to technology and applications

miRNA biomarker discovery

4

Plant miRNAs: New focused genomic solutions

Stem cell overview

5

Microbiome: From identification to characterization

8

long noncoding RNA (lncRNA)

Research tools for the innate immune system

9

PCR Arrays for Pathway Analysis

Tumor heterogeneity analysis

10

NGS: targeted enrichment for translational research

miRNA overview

11

Cancer Stem Cells

Circulating Biomarkers - PreAMP technology

12

Toll-like Receptors in Inflammation

15

Cancer & Immunity Crosstalk

long noncoding RNA (lncRNA)

16

PCR Array Data Analysis Tutorial

Copy number: variation & alteration analysis strategies

17

NGS: targeted enrichment for clinical research

miRNAs expression and quantitation

18

NGS data anlaysis

Cancer Stem Cells

19

Oxidative Stress Research Solutions

22

23

24

25

26

29

30

31

Current Seminar Titles Available:

Focus Title
1.  PCR ArrayPCR Array Data Analysis Tutorial
2.  PCR ArrayPCR Arrays: The Real Pioneer in Real-Time PCR Analysis of Biological Pathways
3.  QPCR IntroductionIntroduction to Real Time PCR (Q-PCR/qPCR/qrt-PCR)
4.  miRNAsThe miRNA revolution: An introduction to microRNA biogenesis, function & analysis
5.  miRNAsmiRNA Quantitation: From experimental design through data analysis
6.  PCR Arrays in ImmunologyExploring the first line of defense: research tools for the innate immune system
7.  Inflammation and TLRToll-like Receptors in Inflammation
8.  Neurodegeneration MechanismsMolecular Mechanisms of Neurodegeneration
9.  miRNAsFunctional analysis of miRNAs
10.  Next-generation sequencingNext-generation sequencing, an introduction to technology and applications
11.  Next-generation sequencingNext-generation sequencing data analysis for genetic profiling
12.  Microbial PCR ArraysMicrobiome: From identification to characterization
13.  miRNAsMicroRNA biomarker discovery - overcoming limiting sample material
14.  Host–Pathogen InteractionsHost–Pathogen Interactions: Molecular Basis and Host Defense Mechanisms
15.  PreAMP for qBiomarker somatic mutationCirculating Biomarkers: New solutions for RNA and DNA
16.  PCR ArraysHow Inflammation Drives Aging: Exploring the Mechanisms
17.  lncRNANew advances in long noncoding RNA (lncRNA) research
18.  Next-generation sequencingNext-Generation Sequencing — Targeted Enrichment Technology in Cancer Research
19.  Next-generation sequencingAdvancing NGS Data Analysis and Interpretation: CLC Cancer Research Workbench and Ingenuity Variant Analysis
20.  Liquid BiopsiesLiquid Biopsies: Current Progress, Challenges, and Solutions
21.  Liquid BiopsiesStep by Step: From a Liquid Biopsy to a Genomic Biomarker
22.  Liquid BiopsiesRole of Long Non-coding RNAs (lncRNAs) in Cancer and microRNA Regulation

PCR Array Data Analysis Tutorial

With a live demonstration using actual PCR array data, learn how easy it is to use our data analysis Web portal to calculate fold-differences in gene expression from your raw real-time PCR threshold cycles.

Duration: 45 minutes followed by Q&A session.

Schedule:

Wednesday, January 28, 2015 at 9:30 AM Eastern    Status: Available Reserve

PCR Arrays: The Real Pioneer in Real-Time PCR Analysis of Biological Pathways

In this 45-minute Webinar, see how the PCR array has led the way toward simple and accurate real-time PCR analysis of relevant biological pathways and diseases. Learn about the stringent performance built into the technology to ensure its sensitivity, specificity, reproducibility, and reliability. Find out how researchers like you have applied PCR arrays to their cancer, immunology, and toxicology research.

Duration: 45 minutes followed by Q&A session.

Schedule:

Wednesday, January 21, 2015 at 9:30 AM Eastern    Status: Available Reserve

Introduction to Real Time PCR (Q-PCR/qPCR/qrt-PCR)

Real-time polymerase chain reaction (qPCR) is the most sensitive and reliable method for the detection and quantification of nucleic acids. This 45-minute webinar introduces the concepts of real-time PCR and how to conduct a real-time PCR assay. The topics that will be covered include an overview of real-time PCR chemistries, protocols, quantification methods, real-time PCR applications, and factors for success. This webinar is for both beginners that are new to real-time PCR as well as experienced users.

Duration: 45 minutes followed by Q&A session.

Schedule:

Wednesday, January 14, 2015 at 9:30 AM Eastern    Status: Available Reserve

The miRNA revolution: An introduction to microRNA biogenesis, function & analysis

miRNA plays a critical role in many biological processes such as differentiation and development, cell signaling, response to infection, and other challenges. Recent studies have shown overwhelming evidence that aberration in miRNA expression is causal or an indicator of many disease processes including cancer. Currently there is a race to find and develop miRNAs as biomarkers and therapeutics. To win the race, it is important to have a strong understanding of miRNA and the challenges of miRNA research. The webinar will cover the biology of miRNA, the key challenges associated with miRNA research, and the latest advances in miRNA research technology.

Duration: 45 minutes followed by Q&A session.

Schedule:

Thursday, January 15, 2015 at 9:30 AM Eastern    Status: Available Reserve

miRNA Quantitation: From experimental design through data analysis

miRNAs play a critical role in many biological processes including neuronal cell fate, hematology, apoptosis and developmental biology. Increasing evidence has shown that aberrations in microRNA regulation are associated with many disease processes. This webinar will discuss the challenges associated with miRNA quantification by real-time PCR, and the latest strategies for miRNA quantification and profiling. The critical parameters of profiling miRNA gene expression will also be presented. Come and learn how you can apply these tools in your miRNA research!

Duration: 45 minutes followed by Q&A session.

Schedule:

Thursday, January 22, 2015 at 9:30 AM Eastern    Status: Available Reserve

Exploring the first line of defense: research tools for the innate immune system

The innate immune system executes crucial and unique functions for host defense against infection. This webinar provides an overview of the most important cellular and molecular players of innate immunity and discusses their functions in a variety of disease states. We also introduce research technologies for exploring innate immune activity in your system through profiling of gene expression and cytokines, signal transduction pathway analysis and more, all in the context.

Duration: 45 minutes followed by Q&A session.

Schedule:

Tuesday, January 27, 2015 at 1:00 PM Eastern    Status: Available Reserve

Toll-like Receptors in Inflammation

"Toll-like receptors (TLRs) have been implicated in both innate and adaptive immunity-induced inflammation, thereby playing critical roles in providing the host with short- and long-term protection against infections.. This webinar will provide an overview of the roles that TLRs play in the regulation of Inflammation and solutions for studying these roles. An overview of TLR-mediated inflammation, the key signaling players involved in TLR-mediated inflammation, and the contribution of TLR-mediated inflammation to various physiological processes will be presented. Please come and learn about the state-of-the-art research tools for analyzing TLR-mediated inflammation and its regulation. "

Duration: 45 minutes followed by Q&A session.

Schedule:

Friday, January 30, 2015 at 1:00 PM Eastern    Status: Available Reserve

Molecular Mechanisms of Neurodegeneration

Common molecular mechanisms and pathways leading to neurodegeneration, such as Alzheimer’s Disease, Parkinson’s Disease, Huntington’s Disease or Multiple Sclerosis, will be discussed in this 45-minute webinar. Research and therapeutic strategies will be presented. Please join us to find out how these discoveries and tools can be used to facilitate your neurodegeneration research.

Duration: 45 minutes followed by Q&A session.

Schedule:

Tuesday, January 6, 2015 at 1:00 PM Eastern    Status: Available Reserve

Functional analysis of miRNAs

Understanding the function and targets of miRNA is important, but challenging research. Since one miRNA can potentially target several genes, finding and validating a specific miRNA-mRNA interaction often involves multiple molecular techniques. In this webinar we will highlight the use of miRNA mimics, inhibitors and target protectors to increase, decrease and adjust the cellular concentration of miRNA and disrupt specific miRNA-mRNA interactions. We will also present a ready-to-use screening tool for identifying miRNA targets in your samples. Lastly, we will show how miRNA expression data can be used to predict mRNA targets and how qPCR can be used to validate predicted interactions.

Duration: 45 minutes followed by Q&A session.

Schedule:

Thursday, January 29, 2015 at 9:30 AM Eastern    Status: Available Reserve

Next-generation sequencing, an introduction to technology and applications

Next-generation sequencing (NGS) technology has revolutionized the study of the genomes, transcriptomes and epigenomes of any species. NGS employs massively parallel sequencing to poduce millions of sequences at once and delivering fast, inexpensive, and accurate genome information. This webinar will provide a technical overview of DNA/RNA preprocessing, template preparation, sequencing, and data analysis. It will also cover the applications for NGS technologies, including guidelines for how to select the technology that will best address your biological question of interest.

Duration: 45 minutes followed by Q&A session.

Schedule:

Monday, January 5, 2015 at 1:00 PM Eastern    Status: Available Reserve

Next-generation sequencing data analysis for genetic profiling

Next-generation employs parallel sequencing process to produce millions of raw sequencing reads. Several steps including assembly, alignment, variant calling, filtering, and annotation are involved in converting raw sequencing reads into an understanding of functional biology. In this webinar, we will discuss the challenges of NGS data analysis and solution provided by the QIAGEN NGS data analysis portal for identifying genetic variants from cell, tissue, and FFPE samples. Using raw sequencing data, we will demonstrate how our web-based data analysis portal can be used to discover known as well as novel variants and derive a biological meaningful interpretation of NGS data.

Duration: 45 minutes followed by Q&A session.

Schedule:

Monday, January 19, 2015 at 1:00 PM Eastern    Status: Available Reserve

Microbiome: From identification to characterization

Duration: 45 minutes followed by Q&A session.

Schedule:

Tuesday, January 20, 2015 at 1:00 PM Eastern    Status: Available Reserve

MicroRNA biomarker discovery - overcoming limiting sample material

This webinar presents an integrated, PCR-based system that reduces the amount of sample required for full miRNome profiling and provides unparalleled reproducibility and precision. This advance opens up new possibilities for biomarker development.

Duration: 45 minutes followed by Q&A session.

Schedule:

Thursday, January 8, 2015 at 9:30 AM Eastern    Status: Available Reserve

Host–Pathogen Interactions: Molecular Basis and Host Defense Mechanisms

Host–pathogen interactions are strikingly complex during infection. This webinar provides an overview of the molecular basis of these intricate interactions; the impact of microbiota on innate and adaptive immunity, metabolism, and insulin resistance; and host defense mechanisms, including newly reported inflammasome-mediated responses and miRNA-mediated responses. Various research tools will be introduced to simplify and streamline each step of studying the host response, enabling analysis of gene expression and regulation, epigenetic modification, genotyping, and signal transduction pathway activation.

Duration: 45 minutes followed by Q&A session.

Schedule:

Tuesday, January 13, 2015 at 1:00 PM Eastern    Status: Available Reserve

Circulating Biomarkers: New solutions for RNA and DNA

The promise of circulating biomarkers is to enable minimally-invasive monitoring of specific molecules that yield predictive or prognostic information. However, that promise cannot be achieved until reliable screening and profiling tools become available to identify specific RNA or DNA molecules with informational value. This process is complicated by the dilution of these valuable molecules by the vast excess of nucleic acids that are not changing or not relevant as biomarkers. QIAGEN has developed solutions to help enrich, amplify and profile nucleic acids that are in circulation, such as tumor-derived DNA that carries a specific mutation or miRNAs that establish a specific expression signature. The webinar will describe solutions from sample preparation to molecule detection that will screen, profile and monitor putative biomarkers. The application examples will highlight new tools for exosomes, cfDNA, and circulating miRNA.

Duration: 45 minutes followed by Q&A session.

Schedule:

Wednesday, January 21, 2015 at 1:00 PM Eastern    Status: Available Reserve

How Inflammation Drives Aging: Exploring the Mechanisms

Many modern diseases, including cancer, cardiovascular disease, diabetes, liver disease, arthritis, and neurodegenerative disease, are related to aging, and intensive research is being conducted to discover both the mechanisms of aging itself as well as its relation to these conditions. This webinar provides an update on how inflammation leads to aging (defined as low regenerative potential) through DNA damage, telomere dysfunction, cellular senescence, and oxidative stress. The NFkB target COX-2 also plays a major role in this process, and recent studies suggest that aging rate may be influenced by the feedback between inflammation, senescence, and ROS. Various assay technologies to tackle the complex signaling pathways in this process will be introduced. Please join us to learn how you can apply these advanced tools to your research!

Duration: 45 minutes followed by Q&A session.

Schedule:

Friday, January 9, 2015 at 1:00 PM Eastern    Status: Available Reserve

New advances in long noncoding RNA (lncRNA) research

"Recent improvements in RNA-sequencing have led to the discovery of thousands of RNAs that do not contain any open reading frames, termed “long noncoding RNA (lncRNA)”. lncRNA expression is thought to be important for the regulation of gene (mRNA) expression through several different mechanisms, some involving competition with transcription and others involving the recruitment of specific epigenetic factors to promoter regions. lncRNA may also indirectly affect gene expression by interacting with miRNA and other cellular factors. In this webinar, we will review what is known about lncRNA and use application examples in cancer research to illustrate how expression profiling is being used to identify lncRNA biomarkers from cells, tissues, blood, and exosomes. "

Duration: 45 minutes followed by Q&A session.

Schedule:

Friday, January 23, 2015 at 1:00 PM Eastern    Status: Available Reserve
Friday, January 30, 2015 at 11:00 AM Eastern    Status: Available Reserve

Next-Generation Sequencing — Targeted Enrichment Technology in Cancer Research

Genetic variance analysis plays a critical role cancer diagnosis, prognosis and treatment of cancer. Low sample volume and poor DNA quality are nagging issues with cancer samples making the results unreliable and expensive. This webinar discusses the most biologically efficient, cost-effective method for successful NGS. The GeneRead DNA QuantiMIZE Kits enable determination of the optimum conditions for targeted enrichment of DNA isolated from biological samples, while the GeneRead DNAseq Panels V2 allow you to quickly and reliably deep sequence your genes of interest. Applications in translational and clinical research will be highlighted.

Duration: 45 minutes followed by Q&A session.

Schedule:

Monday, January 12, 2015 at 1:00 PM Eastern    Status: Available Reserve
Friday, January 16, 2015 at 11:00 AM Eastern    Status: Available Reserve

Advancing NGS Data Analysis and Interpretation: CLC Cancer Research Workbench and Ingenuity Variant Analysis

Deep-sequencing technologies are enabling critical insights into all aspects of cancer genomics. This webinar will discuss two comprehensive informatics solutions — the CLC Cancer Research Workbench and Ingenuity Knowledge Base Variant Analysis platforms. These NGS analysis platforms provide a user-friendly and customizable solution, enabling you to easily narrow down your focus to causal variants and detect and annotate low-frequency somatic variants. We will show the intuitive user interface of CLC Cancer Research Workbench and demonstrate how the rich biological content from Ingenuity Knowledge Base helps you rapidly identify critical variants in your samples.

Duration: 45 minutes followed by Q&A session.

Schedule:

Monday, January 26, 2015 at 1:00 PM Eastern    Status: Available Reserve

Liquid Biopsies: Current Progress, Challenges, and Solutions

A liquid biopsy is often described as a sensitive and specific blood test to detect circulating tumor cells (CTCs). CTCs, shed by both the primary and metastasized tumors, carry specific information about its origin and marker that will enable us to discover new diagnosis, prognosis and therapeutic targets. This webinar will give an overview of the recent progress in exploring the diagnostic, prognostic, and predictive potential of circulating biomarkers, including circulating tumor cells, circulating tumor DNA, miRNAs, lncRNAs, and exosomes. Addressing both biological and technical aspects, we will discuss the isolation and characterization of circulating biomarkers. Challenges and solutions will be discussed.

Duration: 45 minutes followed by Q&A session.

Schedule:

Wednesday, January 7, 2015 at 1:00 PM Eastern    Status: Available Reserve

Step by Step: From a Liquid Biopsy to a Genomic Biomarker

Liquid biopsies enable us to monitor the evolution of genetic aberrations in primary tumors as they shed tumor cells into the circulation. The major limitation of this strategy is the ability to detect these low-frequency genetic aberrations in a consistent manner. The webinar will cover the challenges and solutions associated with each step, beginning with liquid biopsy and moving towards finding a new biomarker.

Duration: 45 minutes followed by Q&A session.

Schedule:

Wednesday, January 14, 2015 at 1:00 PM Eastern    Status: Available Reserve

Role of Long Non-coding RNAs (lncRNAs) in Cancer and microRNA Regulation

It is becoming evident that long non-coding RNAs (lncRNA) play important roles in gene regulation. Many lncRNAs are dysregulated in various cancer types and closely related to tumorigenesis, metastasis, and prognosis or diagnosis. This webinar will discuss the regulation and functional roles of lncRNA in cancers, with a particular focus on how lncRNAs impact microRNA expression and function. A new qPCR-based lncRNA platform for lncRNA detection and profiling will be introduced. An application for serum lncRNA detection as a potential biomarker of lung cancer will also be highlighted.

Duration: 45 minutes followed by Q&A session.

Schedule:

Wednesday, January 28, 2015 at 1:00 PM Eastern    Status: Available Reserve

Note: Viewers will be asked to register before viewing the previously recorded webinars.