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Home > Resources > Publications
Publications Citing SABiosciences Products
RT² Profiler PCR Arrays
| Angiogenesis |
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Airoldi I, Di Carlo E, Cocco C, Taverniti G, D'Antuono T,
Ognio E, Watanabe M, Ribatti D, Pistoia V. Endogenous IL-12 triggers an
antiangiogenic program in melanoma cells. Proc Natl Acad Sci U S A. 2007
Mar 6;104(10):3996-4001. Epub 2007 Feb 23 |
PUBMED |
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Basile DP, Fredrich K, Chelladurai B, Leonard EC, Parrish
AR Renal ischemia reperfusion inhibits VEGF expression and induces
ADAMTS-1, a novel VEGF inhibitor. Am J Physiol Renal Physiol. 2008
Apr;294(4):F928-36. Epub 2008 Feb 13. |
PUBMED |
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Rangel-Moreno J, Hartson L, Navarro C, Gaxiola M, Selman
M, Randall TD. Inducible bronchus-associated lymphoid tissue (iBALT) in
patients with pulmonary complications of rheumatoid arthritis. J Clin
Invest. 2006 Dec;116(12):3183-94. |
PUBMED |
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van Beem RT, Noort WA, Voermans C, Kleijer M, ten Brinke
A, van Ham SM, van der Schoot CE, Zwaginga JJ The presence of activated
CD4(+) T cells is essential for the formation of colony-forming
unit-Endothelial cells by CD14(+) Cells. J Immunol. 2008 Apr
1;180(7):5141-8 |
PUBMED |
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| Apoptosis |
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Dickson EW, Hogrefe CP, Ludwig PS, Ackermann LW, Stoll LL,
Denning GM Exercise Enhances Myocardial Ischemic Tolerance via an Opioid
Receptor-Dependent Mechanism. Am J Physiol Heart Circ Physiol. 2007 Oct
19; [Epub ahead of print] |
PUBMED |
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Lai YM, Mohammed KA, Nasreen N, Baumuratov A, Bellew BF,
Antony VB. Induction of cell cycle arrest and apoptosis by BCG infection
in cultured human bronchial airway epithelial cells. Am J Physiol Lung
Cell Mol Physiol. 2007 Aug;293(2):L393-401. Epub 2007 May 25. |
PUBMED |
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Raeder S, Utheim TP, Utheim OA, Nicolaissen B, Roald B,
Cai Y, Haug K, Kvalheim A, Messelt EB, Drolsum L, Reed JC, Lyberg T.
Effects of organ culture and Optisol-GS storage on structural integrity,
phenotypes, and apoptosis in cultured corneal epithelium. Invest
Ophthalmol Vis Sci. 2007 Dec;48(12):5484-93 |
PUBMED |
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Zhan Q, Signoretti S, Whitaker-Menezes D, Friedman TM,
Korngold R, Murphy GF. Cytokeratin15-positive basal epithelial cells
targeted in graft-versus-host disease express a constitutive
antiapoptotic phenotype. J Invest Dermatol. 2007 Jan;127(1):106-15. Epub
2006 Oct 12. |
PUBMED |
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| Cell
Cycle |
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Chen N, Ye XC, Chu K, Navone NM, Sage EH, Yu-Lee LY,
Logothetis CJ, Lin SH. A secreted isoform of ErbB3 promotes osteonectin
expression in bone and enhances the invasiveness of prostate cancer
cells. Cancer Res. 2007 Jul 15;67(14):6544-8 |
PUBMED |
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Chen S, Sims GP, Chen XX, Gu YY, Chen S, Lipsky PE.
Modulatory effects of 1,25-dihydroxyvitamin D3 on human B cell
differentiation. J Immunol. 2007 Aug 1;179(3):1634-47. |
PUBMED |
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Lu SY, Sontag DP, Detillieux KA, Cattini PA. FGF-16 is
released from neonatal cardiac myocytes and alters growth-related
signaling: a possible role in postnatal development. Am J Physiol Cell
Physiol. 2008 May;294(5):C1242-9. Epub 2008 Mar 12 |
PUBMED |
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| Chemokines
& Receptors |
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Klopp AH, Spaeth EL, Dembinski JL, Woodward WA, Munshi A,
Meyn RE, Cox JD, Andreeff M, Marini FC Tumor irradiation increases the
recruitment of circulating mesenchymal stem cells into the tumor
microenvironment. Cancer Res. 2007 Dec 15;67(24):11687-95. |
PUBMED |
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Miselis NR, Wu ZJ, Van Rooijen N, Kane AB Targeting
tumor-associated macrophages in an orthotopic murine model of diffuse
malignant mesothelioma. Mol Cancer Ther. 2008 Apr;7(4):788-99. Epub 2008
Mar 28 |
PUBMED |
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Sinha S, Subramanian S, Proctor TM, Kaler LJ, Grafe M,
Dahan R, Huan J, Vandenbark AA, Burrows GG, Offner H. A promising
therapeutic approach for multiple sclerosis: recombinant T-cell receptor
ligands modulate experimental autoimmune encephalomyelitis by reducing
interleukin-17 production and inhibiting migration of encephalitogenic
cells into the CNS J Neurosci. 2007 Nov 14;27(46):12531-9. |
PUBMED |
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Sze SK, de Kleijn DP, Lai RC, Khia Way Tan E, Zhao H, Yeo
KS, Low TY, Lian Q, Lee CN, Mitchell W, El Oakley RM, Lim SK.
Elucidating the secretion proteome of human embryonic stem cell-derived
mesenchymal stem cells. Mol Cell Proteomics. 2007 Oct;6(10):1680-9. Epub
2007 Jun 11. |
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| Common
Cytokines |
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Gude N, Muraski J, Rubio M, Kajstura J, Schaefer E,
Anversa P, Sussman MA. Akt promotes increased cardiomyocyte cycling and
expansion of the cardiac progenitor cell population. Circ Res. 2006 Aug
18;99(4):381-8. Epub 2006 Jul 13. |
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Keskin DB, Allan DS, Rybalov B, Andzelm MM, Stern JN,
Kopcow HD, Koopman LA, Strominger JL. TGFbeta promotes conversion of
CD16+ peripheral blood NK cells into CD16- NK cells with similarities to
decidual NK cells. Proc Natl Acad Sci U S A. 2007 Feb 27;104(9):3378-83.
Epub 2007 Feb 20. |
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Sze SK, de Kleijn DP, Lai RC, Khia Way Tan E, Zhao H, Yeo
KS, Low TY, Lian Q, Lee CN, Mitchell W, El Oakley RM, Lim SK.
Elucidating the secretion proteome of human embryonic stem cell-derived
mesenchymal stem cells. Mol Cell Proteomics. 2007 Oct;6(10):1680-9. Epub
2007 Jun 11. |
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| Custom |
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Bowers RR, Kim JW, Otto TC, Lane MD. Stable stem cell
commitment to the adipocyte lineage by inhibition of DNA methylation:
Role of the BMP-4 gene. Proc Natl Acad Sci U S A. 2006 Aug 17; [Epub
ahead of print] |
PUBMED |
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Torcia MG, Santarlasci V, Cosmi L, Clemente A, Maggi L,
Mangano VD, Verra F, Bancone G, Nebie I, Sirima BS, Liotta F, Frosali F,
Angeli R, Severini C, Sannella AR, Bonini P, Lucibello M, Maggi E,
Garaci E, Coluzzi M, Cozzolino F, Annunziato F, Romagnani S, Modiano D.
Functional deficit of T regulatory cells in Fulani, an ethnic group with
low susceptibility to Plasmodium falciparum malaria. Proc Natl Acad Sci
U S A. 2008 Jan 15;105(2):646-51. Epub 2008 Jan 3 |
PUBMED |
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| Drug
Metabolism: Phase I Enzymes |
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Ning B, Dial S, Sun Y, Wang J, Yang J, Guo L Systematic
and simultaneous gene profiling of 84 drug-metabolizing genes in primary
human hepatocytes J Biomol Screen. 2008 Mar;13(3):194-201. Epub 2008 Feb
12 |
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| Extracellular
Matrix & Adhesion Molecules |
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Collins M, Hurford R, Chao Y, Patrick C, Langford TD.
Variability in Virus and in Host During HIV-1 Infection. Horn of Africa
Journal of AIDS. 2006 Volume III, Issue I:38-46. |
PUBMED |
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Gelain F, Bottai D, Vescovi A, Zhang S. Designer
self-assembling Peptide nanofiber scaffolds for adult mouse neural stem
cell 3-dimensional cultures. PLoS ONE. 2006 Dec 27;1:e119. |
PUBMED |
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Johansen LD, Naumanen T, Knudsen A, Westerlund N, Gromova
I, Junttila M, Nielsen C, Bottzauw T, Tolkovsky A, Westermarck J,
Coffey ET, Jaattela M, Kallunki T. IKAP localizes to membrane
ruffles with filamin A and regulates actin cytoskeleton organization and
cell migration. J Cell Sci. 2008 Mar 15;121(Pt 6):854-64. Epub 2008 Feb
26. |
PUBMED |
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Nacu N, Luzina IG, Highsmith K, Lockatell V, Pochetuhen
K, Cooper ZA, Gillmeister MP, Todd NW, Atamas SP Macrophages produce TGF-beta-induced
(beta-ig-h3) following ingestion of apoptotic cells and regulate MMP14
levels and collagen turnover in fibroblasts J Immunol. 2008 Apr
1;180(7):5036-44 |
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Oumouna-Benachour K, Hans CP, Suzuki Y, Naura A, Datta R,
Belmadani S, Fallon K, Woods C, Boulares AH. Poly(ADP-ribose) polymerase
inhibition reduces atherosclerotic plaque size and promotes factors of
plaque stability in apolipoprotein E-deficient mice: effects on
macrophage recruitment, nuclear factor-kappaB nuclear translocation, and
foam cell death. Circulation. 2007 May 8;115(18):2442-50. Epub 2007 Apr
16. PUBMED |
PUBMED |
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Shinoda Y, Ogata N, Higashikawa A, Manabe I, Shindo T,
Yamada T, Kugimiya F, Ikeda T, Kawamura N, Kawasaki Y, Tsushima K,
Takeda N, Nagai R, Hoshi K, Nakamura K, Chung UI, Kawaguchi H. Kruppel-like
factor 5 causes cartilage degradation through transactivation of matrix
metalloproteinase 9. J Biol Chem. 2008 Jul 10. [Epub ahead of
print] |
PUBMED |
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Tapia A, Salamonsen LA, Manuelpillai U, Dimitriadis E.
Leukemia inhibitory factor promotes human first trimester extravillous
trophoblast adhesion to extracellular matrix and secretion of tissue
inhibitor of metalloproteinases-1 and -2. Hum Reprod. 2008
Aug;23(8):1724-32. Epub 2008 May 20. |
PUBMED |
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Yen JH, Khayrullina T, Ganea D. PGE2-induced
metalloproteinase-9 is essential for dendritic cell migration Blood.
2007 Oct 9; [Epub ahead of print] PUBMED |
PUBMED |
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Zauli G, Corallini F, Bossi F, Fischetti F, Durigutto P,
Celeghini C, Tedesco F, Secchiero P. Osteoprotegerin increases leukocyte
adhesion to endothelial cells both in vitro and in vivo. Blood. 2007 Jul
15;110(2):536-43. Epub 2007 Mar 15. |
PUBMED |
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Zauli G, Corallini F, Bossi F, Fischetti F, Durigutto P,
Celeghini C, Tedesco F, Secchiero P. Osteoprotegerin increases leukocyte
adhesion to endothelial cells both in vitro and in vivo. Blood. 2007 Jul
15;110(2):536-43. Epub 2007 Mar 15. |
PUBMED |
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| Endothelial
Cell Biology |
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Li Z, Suzuki Y, Huang M, Cao F, Xie X, Connolly AJ, Yang
PC, Wu JC Comparison of Reporter Gene and Iron Particle Labeling for
Tracking Fate of Human Embryonic Stem Cells and Differentiated
Endothelial Cells in Living Subjects. Stem Cells. 2008 Apr;26(4):864-73.
Epub 2008 Jan 24 |
PUBMED |
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| Hypoxia
Signaling |
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Wendler CC, Amatya S, McClaskey C, Ghatpande S, Fredholm
BB, Rivkees SA. A1 adenosine receptors play an essential role in
protecting the embryo against hypoxia. Proc Natl Acad Sci U S A. 2007
Jun 5;104(23):9697-702. Epub 2007 May 23 |
PUBMED |
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| Inflammatory
Cytokines & Receptors |
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Aubin E, Lemieux R, Bazin R. Absence of cytokine
modulation following therapeutic infusion of intravenous immunoglobulin
or anti-red blood cell antibodies in a mouse model of immune
thrombocytopenic purpura. Br J Haematol. 2007 Mar;136(6):837-43. |
PUBMED |
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Dickson EW, Hogrefe CP, Ludwig PS, Ackermann LW, Stoll LL,
Denning GM Exercise Enhances Myocardial Ischemic Tolerance via an Opioid
Receptor-Dependent Mechanism. Am J Physiol Heart Circ Physiol. 2007 Oct
19; [Epub ahead of print] |
PUBMED |
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Lakshmanan U, Porter AG Caspase-4 interacts with TNF
receptor-associated factor 6 and mediates lipopolysaccharide-induced NF-kappaB-dependent
production of IL-8 and CC chemokine ligand 4 (macrophage-inflammatory
protein-1 ). J Immunol. 2007 Dec 15;179(12):8480-90 |
PUBMED |
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Rangel-Moreno J, Hartson L, Navarro C, Gaxiola M, Selman
M, Randall TD. Inducible bronchus-associated lymphoid tissue (iBALT) in
patients with pulmonary complications of rheumatoid arthritis. J Clin
Invest. 2006 Dec;116(12):3183-94. |
PUBMED |
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Sze SK, de Kleijn DP, Lai RC, Khia Way Tan E, Zhao H, Yeo
KS, Low TY, Lian Q, Lee CN, Mitchell W, El Oakley RM, Lim SK.
Elucidating the secretion proteome of human embryonic stem cell-derived
mesenchymal stem cells. Mol Cell Proteomics. 2007 Oct;6(10):1680-9. Epub
2007 Jun 11. |
PUBMED |
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| Interferon α, β Response |
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Tilton JC, Manion MM, Luskin MR, Johnson AJ, Patamawenu
AA, Hallahan CW, Cogliano-Shutta NA, Mican JM, Davey RT Jr, Kottilil S,
Lifson JD, Metcalf JA, Lempicki RA, Connors M. Human immunodeficiency
virus viremia induces plasmacytoid dendritic cell activation in vivo and
diminished alpha interferon production in vitro. J Virol. 2008
Apr;82(8):3997-4006. Epub 2008 Feb 6 |
PUBMED |
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| JAK
/ STAT Signaling |
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Albanesi C, Fairchild HR, Madonna S, Scarponi C, De Pit?O,
Leung DY, Howell MD. IL-4 and IL-13 negatively regulate TNF-alpha- and
IFN-gamma-induced beta-defensin expression through STAT-6, suppressor of
cytokine signaling (SOCS)-1, and SOCS-3. J Immunol. 2007 Jul
15;179(2):984-92. |
PUBMED |
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Duechting A, Tschope C, Kaiser H, Lamkemeyer T,
Tanaka N, Aberle S, Lang F, Torresi J, Kandolf R, Bock CT. Human
Parvovirus B19 NS1 Protein Modulates Inflammatory Signaling by
Activation of STAT3/PIAS3 in Human Endothelial Cells. J Virol. 2008 Jun
11. [Epub ahead of print] |
PUBMED |
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Sze SK, de Kleijn DP, Lai RC, Khia Way Tan E, Zhao H, Yeo
KS, Low TY, Lian Q, Lee CN, Mitchell W, El Oakley RM, Lim SK.
Elucidating the secretion proteome of human embryonic stem cell-derived
mesenchymal stem cells. Mol Cell Proteomics. 2007 Oct;6(10):1680-9. Epub
2007 Jun 11. |
PUBMED |
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| MAP
Kinase Signaling |
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Ruettger A, Schueler S, Mollenhauer JA, Wiederanders B.
Cathepsins B, K and L are regulated by a defined collagen type II
peptide via activation of classical protein kinase C and p38 MAP kinase
in articular chondrocytes. J Biol Chem. 2007 Nov 8; [Epub ahead of
print] |
PUBMED |
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Singh S, Yin X, Pisano MM, Greene RM. Molecular profiles
of mitogen activated protein kinase signaling pathways in orofacial
development. Birth Defects Res A Clin Mol Teratol. 2007 Jan;79(1):35-44.
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PUBMED |
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| NFκB Signaling |
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Chen N, Ye XC, Chu K, Navone NM, Sage EH,
Yu-Lee LY, Logothetis CJ, Lin SH. A secreted isoform of ErbB3 promotes
osteonectin expression in bone and enhances the invasiveness of prostate
cancer cells. Cancer Res. 2007 Jul 15;67(14):6544-8. |
PUBMED |
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Chen S, Sims GP, Chen XX, Gu YY, Chen S,
Lipsky PE. Modulatory effects of 1,25-dihydroxyvitamin D3 on human B
cell differentiation. J Immunol. 2007 Aug 1;179(3):1634-47. |
PUBMED |
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Sze SK, de Kleijn DP, Lai RC, Khia Way Tan E,
Zhao H, Yeo KS, Low TY, Lian Q, Lee CN, Mitchell W, El Oakley RM, Lim
SK. Elucidating the secretion proteome of human embryonic stem
cell-derived mesenchymal stem cells. Mol Cell Proteomics. 2007
Oct;6(10):1680-9. Epub 2007 Jun 11. |
PUBMED |
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| Osteogenesis |
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Gouttenoire J, Valcourt U, Bougault C, Aubert-Foucher E,
Arnaud E, Giraud L, Mallein-Gerin F. Knockdown of the intraflagellar
transport protein IFT46 stimulates selective gene expression in mouse
chondrocytes and affects early development in zebrafish. J Biol Chem.
2007 Oct 19;282(42):30960-73. Epub 2007 Aug 24 |
PUBMED |
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Wescott DC, Pinkerton MN, Gaffey BJ, Beggs KT, Milne TJ,
Meikle MC. Osteogenic gene expression by human periodontal ligament
cells under cyclic tension. J Dent Res. 2007 Dec;86(12):1212-6 |
PUBMED |
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| p53
Signaling |
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Brockschmidt C, Hirner H, Huber N, Eismann T, Hillenbrand
A, Giamas G, Radunsky B, Ammerpohl O, Bohm B, Henne-Bruns D, Kalthoff H,
Leithauser F, Trauzold A, Knippschild U Anti-apoptotic and
growth-stimulatory functions of CK1 delta and epsilon in ductal
adenocarcinoma of the pancreas are inhibited by IC261 in vitro and in
vivo. Gut. 2008 Jun;57(6):799-806. Epub 2008 Jan 18. |
PUBMED |
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| Stem
Cell |
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Tjandra SS, Hsu C, Goh I, Gurung A, Poon R,
Nadesan P, Alman BA IFN-{beta} signaling positively regulates
tumorigenesis in aggressive fibromatosis, potentially by modulating
mesenchymal progenitors. Cancer Res. 2007 Aug 1;67(15):7124-31. |
PUBMED |
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| Th1,
Th2, Th3 |
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Torcia MG, Santarlasci V, Cosmi L, Clemente A, Maggi L,
Mangano VD, Verra F, Bancone G, Nebie I, Sirima BS, Liotta F, Frosali F,
Angeli R, Severini C, Sannella AR, Bonini P, Lucibello M, Maggi E,
Garaci E, Coluzzi M, Cozzolino F, Annunziato F, Romagnani S, Modiano D.
Functional deficit of T regulatory cells in Fulani, an ethnic group with
low susceptibility to Plasmodium falciparum malaria. Proc Natl Acad Sci
U S A. 2008 Jan 15;105(2):646-51. Epub 2008 Jan 3 |
PUBMED |
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| TH17
for Autoimmunity & Inflammation |
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Lochner M, Peduto L, Cherrier M, Sawa S, Langa F, Varona
R, Riethmacher D, Si-Tahar M, Di Santo JP, Eberl G. In vivo equilibrium
of proinflammatory IL-17+ and regulatory IL-10+ Foxp3+ RORgamma t+ T
cells. J Exp Med. 2008 Jun 9;205(6):1381-93. Epub 2008 May 26 |
PUBMED |
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| Toll-Like
Receptor Signaling |
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Brant KA, Fabisiak JP. Nickel Alterations of
TLR2-Dependent Chemokine Profiles in Lung Fibroblasts are Mediated by
COX-2. Am J Respir Cell Mol Biol. 2007 Dec 20 [Epub ahead of
print] |
PUBMED |
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Ornatowska M, Azim AC, Wang X, Christman JW, Xiao L, Joo
M, Sadikot RT. Functional genomics of silencing TREM-1 on TLR4 signaling
in macrophages. Am J Physiol Lung Cell Mol Physiol. 2007
Dec;293(6):L1377-84. Epub 2007 Sep 28 |
PUBMED |
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Tilton JC, Manion MM, Luskin MR, Johnson AJ, Patamawenu
AA, Hallahan CW, Cogliano-Shutta NA, Mican JM, Davey RT Jr, Kottilil S,
Lifson JD, Metcalf JA, Lempicki RA, Connors M. Human immunodeficiency
virus viremia induces plasmacytoid dendritic cell activation in vivo and
diminished alpha interferon production in vitro. J Virol. 2008
Apr;82(8):3997-4006. Epub 2008 Feb 6 |
PUBMED |
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Tomchuck SL, Zwezdaryk KJ, Coffelt SB,
Waterman RS, Danka ES, Scandurro AB Toll-Like Receptors on Human
Mesenchymal Stem Cells Drive their Migration and Immunomodulating
Responses. Stem Cells. 2007 Oct 4; [Epub ahead of print] |
PUBMED |
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West J, Damania B Upregulation of the TLR3 pathway by
Kaposi's sarcoma-associated herpesvirus during primary infection. J
Virol. 2008 Jun;82(11):5440-9. Epub 2008 Mar 26 |
PUBMED |
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| Toxicology |
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Joseph, P. et al. Heme-oxygenase 1 Gene Expression is a
Marker for Hexavalent Chromium-Induced Stress and Toxicity in Human
Dermal Fibroblasts. Toxicol. Sci., Jun 2008; 103: 325 - 334. |
PUBMED |
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Marshall, N.B, et al. Functional Characterization and
Gene Expression Analysis of CD4+CD25+ Regulatory T Cells Generated in
Mice Treated with 2,3,7,8-Tetrachlorodibenzo-p-Dioxin. J. Immunol., Aug
2008; 181: 2382 - 2391. |
PUBMED |
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Ning, B. et al. Systematic and Simultaneous Gene
Profiling of 84 Drug-Metabolizing Genes in Primary Human Hepatocytes. J
Biomol Screen, Mar 2008; 13: 194 - 201. |
PUBMED |
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| Tumor Metastasis |
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Wang J, Shiozawa Y, Wang J, Wang Y, Jung Y, Pienta KJ,
Mehra R, Lober R, Taichman RS The role of CXCR7/RDC1 as a chemokine
receptor for CXCL12/ SDF-1 in prostate cancer. J Biol Chem. 2007 Dec 5 [Epub
ahead of print] |
PUBMED |
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| WNT
Signaling |
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Aslanidi G, Kroutov V, Philipsberg G, Lamb K,
Campbell-Thompson M, Walter GA, Kurenov S, Ignacio Aguirre J, Keller P,
Hankenson K, Macdougald OA, Zolotukhin S. Ectopic expression of Wnt10b
decreases adiposity and improves glucose homeostasis in obese rats. Am J
Physiol Endocrinol Metab. 2007 Sep;293(3):E726-36. Epub 2007 Jun 19 |
PUBMED |
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Giuliani N, Morandi F, Tagliaferri S,
Lazzaretti M, Donofrio G, Bonomini S, Sala R, Mangoni M, Rizzoli V.
Production of wnt inhibitors by myeloma cells: potential effects on
canonical wnt pathway in the bone microenvironment. Cancer Res. 2007 Aug
15;67(16):7665-74. |
PUBMED |
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Guo W, Flanagan J, Jasuja R, Kirkland J, Jiang L, Bhasin
S. The Effects of Myostatin on Adipogenic Differentiation of Human Bone
Marrow-derived Mesenchymal Stem Cells Are Mediated through
Cross-communication between Smad3 and Wnt/{beta}-Catenin Signaling
Pathways. J Biol Chem. 2008 Apr 4;283(14):9136-45. Epub 2008 Jan 18. |
PUBMED |
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Hidestrand M, Richards-Malcolm S, Gurley CM, Nolen G,
Grimes B, Waterstrat A, Zant GV, Peterson CA. Sca-1-expressing
nonmyogenic cells contribute to fibrosis in aged skeletal muscle. J
Gerontol A Biol Sci Med Sci. 2008 Jun;63(6):566-79. |
PUBMED |
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Welters HJ, Oknianska A, Erdmann KS, Ryffel GU, Morgan NG
The protein tyrosine phosphatase-BL, modulates pancreatic beta-cell
proliferation by interaction with the Wnt signaling pathway. J
Endocrinol. 2008 Jun;197(3):543-52. Epub 2008 Apr 15 |
PUBMED |
BACK TO TOP
SureSilencing shRNA Plasmids
| Cancer |
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Baritaki S, Huerta-Yepez S, Sakai T, Spandidos DA,
Bonavida B. Chemotherapeutic drugs sensitize cancer cells to
TRAIL-mediated apoptosis: up-regulation of DR5 and inhibition of Yin
Yang 1. Mol Cancer Ther. 2007 Apr;6(4):1387-99. |
PUBMED |
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Demorrow S, Francis H, Gaudio E, Ueno Y, Venter J, Onori
P, Franchitto A, Vaculin B, Vaculin S, Alpini G Anandamide inhibits
cholangiocyte hyperplastic proliferation via activation of thioredoxin
1/redox factor 1 and AP-1 activation. Am J Physiol Gastrointest Liver
Physiol. 2007 Dec 20 [Epub ahead of print] |
PUBMED |
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Demorrow S, Glaser S, Francis H, Venter J, Vaculin B,
Vaculin S, Alpini G. Opposing actions of endocannabinoids on
cholangiocarcinoma growth: Recruitment of fas and fas ligand to lipid
rafts. J Biol Chem. 2007 Apr 27;282(17):13098-113. Epub 2007 Feb 28. |
PUBMED |
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Dhakshinamoorthy S, Sridharan SR, Li L, Ng PY, Boxer LM,
Porter AG Protein/DNA arrays identify nitric oxide-regulated cis-element
and trans-factor activities some of which govern neuroblastoma cell
viability. Nucleic Acids Res. 2007;35(16):5439-51. Epub 2007 Aug 15. |
PUBMED |
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Dimple C, Nair SS, Rajhans R, Pitcheswara PR, Liu J,
Balasenthil S, Le XF, Burow ME, Auersperg N, Tekmal RR, Broaddus RR,
Vadlamudi RK. Role of PELP1/MNAR signaling in ovarian tumorigenesis.
Cancer Res. 2008 Jun 15;68(12):4902-9. |
PUBMED |
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Guo Y, Xie J, Rubin E, Tang YX, Lin F, Zi X, Hoang BH.
Frzb, a secreted Wnt antagonist, decreases growth and invasiveness of
fibrosarcoma cells associated with inhibition of Met signaling. Cancer
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Horak CE, Lee JH, Elkahloun AG, Boissan M, Dumont S, Maga
TK, Arnaud-Dabernat S, Palmieri D, Stetler-Stevenson WG, Lacombe ML,
Meltzer PS, Steeg PS. Nm23-H1 suppresses tumor cell motility by
down-regulating the lysophosphatidic acid receptor EDG2. Cancer Res.
2007 Aug 1;67(15):7238-46. |
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McFate T, Mohyeldin A, Lu H, Thakar J, Henriques J, Halim
ND, Wu H, Schell MJ, Tsang TM, Teahan O, Zhou S, Califano JA, Jeoung NH,
Harris RA, Verma A. Pyruvate dehydrogenase complex activity controls
metabolic and malignant phenotype in cancer cells. J Biol Chem. 2008 Jun
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McGowan PM, Ryan BM, Hill AD, McDermott E, O'Higgins N,
Duffy MJ. ADAM-17 expression in breast cancer correlates with variables
of tumor progression. Clin Cancer Res. 2007 Apr 15;13(8):2335-43 |
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Rajhans R, Nair HB, Nair SS, Cortez V, Ikuko K, Kirma NB,
Zhou D, Holden AE, Brann DW, Chen S, Tekmal RR, Vadlamudi RK. Modulation
of in situ Estrogen Synthesis by PELP1: Potential ER Autocrine Signaling
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Tirado OM, Mateo-Lozano S, Villar J, Dettin LE, Llort A,
Gallego S, Ban J, Kovar H, Notario V. Caveolin-1 (CAV1) is a target of
EWS/FLI-1 and a key determinant of the oncogenic phenotype and
tumorigenicity of Ewing's sarcoma cells. Cancer Res. 2006 Oct
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Zhao S, Venkatasubbarao K, Lazor JW, Sperry J, Jin C, Cao
L, Freeman JW Inhibition of STAT3 Tyr705 phosphorylation by Smad4
suppresses transforming growth factor beta-mediated invasion and
metastasis in pancreatic cancer cells. Cancer Res. 2008 Jun
1;68(11):4221-8 |
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| Cardiovascular Disease |
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Torella D, Curcio A, Gasparri C, Galuppo V, De Serio D,
Surace FC, Cavaliere AL, Leone A, Coppola C, Ellison GM, Indolfi C.
Fludarabine prevents smooth muscle proliferation in vitro and neointimal
hyperplasia in vivo through specific inhibition of STAT-1 activation Am
J Physiol Heart Circ Physiol. 2007 Jun;292(6):H2935-43. Epub 2007 Feb 9.
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| Immunology |
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Lawson BR, Manenkova Y, Ahamed J, Chen X, Zou JP, Baccala
R, Theofilopoulos AN, Yuan C. Inhibition of transmethylation
down-regulates CD4 T cell activation and curtails development of
autoimmunity in a model system. J Immunol. 2007 Apr 15;178(8):5366-74. |
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Wang J, Barke RA, Charboneau R, Schwendener R, Roy S.
Morphine Induces Defects in Early Response of Alveolar Macrophages to
Streptococcus pneumoniae by Modulating TLR9-NF-{kappa}B Signaling. J
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| Neuroscience |
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Uo T, Kinoshita Y, Morrison RS. Apoptotic actions of p53
require transcriptional activation of PUMA and do not involve a direct
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| Signal Transduction |
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Ciccone NA, Lacza CT, Hou MY, Gregory SJ, Kam KY, Xu S,
Kaiser UB. A Composite Element that Binds Basic Helix Loop Helix and
Basic Leucine Zipper Transcription Factors Is Important for GnRH
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Xue M, Campbell D, Jackson CJ Protein C is an autocrine
growth factor for human skin keratinocytes J Biol Chem. 2007 May
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| Stem Cells |
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Guo Y, Mantel C, Hromas RA, Broxmeyer HE Oct-4 is
critical for survival/antiapoptosis of murine embryonic stem cells
subjected to stress: effects associated with Stat3/survivin. Stem Cells.
2008 Jan;26(1):30-4. Epub 2007 Oct 11 |
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Liou JY, Ellent DP, Lee S, Goldsby J, Ko BS, Matijevic N,
Huang JC, Wu KK. Cyclooxygenase-2-derived prostaglandin e2 protects
mouse embryonic stem cells from apoptosis. Stem Cells. 2007
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Wang XY, Yin Y, Yuan H, Sakamaki T, Okano H, Glazer RI.
Musashi1 modulates mammary progenitor cell expansion through proliferin-mediated
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RT² PCR Primer Sets
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Acuff HB, Sinnamon M, Fingleton B, Boone B,
Levy SE, Chen X, Pozzi A, Carbone DP, Schwartz DR, Moin K, Sloane BF,
Matrisian LM. Analysis of host- and tumor-derived proteinases using a
custom dual species microarray reveals a protective role for stromal
matrix metalloproteinase-12 in non-small cell lung cancer. Cancer Res.
2006 Aug 15;66(16):7968-75. |
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Albanesi C, Fairchild HR, Madonna S, Scarponi
C, De Pit?O, Leung DY, Howell MD. IL-4 and IL-13 negatively regulate TNF-alpha-
and IFN-gamma-induced beta-defensin expression through STAT-6,
suppressor of cytokine signaling (SOCS)-1, and SOCS-3. J Immunol. 2007
Jul 15;179(2):984-92 |
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Alikhani M, Alikhani Z, Graves DT. FOXO1
functions as a master switch that regulates gene expression necessary
for tumor necrosis factor-induced fibroblast apoptosis. J Biol Chem.
2005 Apr 1;280(13):12096-102. Epub 2005 Jan 4. |
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Andarawewa KL, Erickson AC, Chou WS, Costes
SV, Gascard P, Mott JD, Bissell MJ, Barcellos-Hoff MH. Ionizing
radiation predisposes nonmalignant human mammary epithelial cells to
undergo transforming growth factor beta induced epithelial to
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Angeloni C, Leoncini E, Malaguti M, Angelini S, Hrelia P,
Hrelia S. Role of quercetin in modulating rat cardiomyocyte gene
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Artaza JN, Singh R, Ferrini MG, Braga M, Tsao J,
Gonzalez-Cadavid NF Myostatin promotes a fibrotic phenotypic switch in
multipotent C3H 10T1/2 cells without affecting their differentiation
into myofibroblasts J Endocrinol. 2008 Feb;196(2):235-49
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Asprodites N, Zheng L, Geng D, Velasco-Gonzalez C,
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Augustus AS, Buchanan J, Addya S, Rengo G, Pestell R,
Fortina P, Koch WJ, Bensadoun A, Abel ED, Lisanti MP. Substrate Uptake
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Beinfeld MC, Blum A, Vishnuvardhan D, Fanous
S, Marchand JE Cholecystokinin levels in prohormone convertase 2
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region-specific alterations J Biol Chem. 2005 Nov 18;280(46):38410-5.
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Beretsos P, Loutradis D, Koussoulakos S,
Margaritis LH, Kiapekou E, Mastorakos G, Papaspirou I, Makris N,
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Binnerts ME, Kim KA, Bright JM, Patel SM,
Tran K, Zhou M, Leung JM, Liu Y, Lomas WE 3rd, Dixon M, Hazell SA, Wagle
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Bird AD, Tan KH, Olsson PF, Zieba M, Flecknoe
SJ, Liddicoat DR, Mollard R, Hooper SB, Cole TJ. Identification of
glucocorticoid-regulated genes that control cell proliferation during
murine respiratory development. J Physiol. 2007 Nov 15;585(Pt
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Boer B, Kopp J, Mallanna S, Desler M,
Chakravarthy H, Wilder PJ, Bernadt C, Rizzino A. Elevating the levels of
Sox2 in embryonal carcinoma cells and embryonic stem cells inhibits the
expression of Sox2:Oct-3/4 target genes. Nucleic Acids Res.
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Bossard C, Bresson D, Polishchuk RS, Malhotra V. Dimeric
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Brandl K, Plitas G, Schnabl B, DeMatteo RP,
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gamma and protect mice against intestinal Listeria monocytogenes
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Brest P, Gustafsson M, Mossberg AK, Gustafsson L,
Duringer C, Hamiche A, Svanborg C. Histone deacetylase inhibitors
promote the tumoricidal effect of HAMLET. Cancer Res. 2007 Dec
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Brown JM, Swindle EJ, Kushnir-Sukhov NM,
Holian A, Metcalfe DD. Silica-Directed Mast Cell Activation Is Enhanced
by Scavenger Receptors. Am J Respir Cell Mol Biol. 2007 Jan;36(1):43-52.
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Burgess SJ, Marusina AI, Pathmanathan I,
Borrego F, Coligan JE IL-21 Down-Regulates NKG2D/DAP10 Expression on
Human NK and CD8+ T Cells J Immunol. 2006 Feb 1;176(3):1490-7 |
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Chen S, Sims GP, Chen XX, Gu YY, Chen S,
Lipsky PE. Modulatory effects of 1,25-dihydroxyvitamin D3 on human B
cell differentiation. J Immunol. 2007 Aug 1;179(3):1634-47 |
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Cheng W, Jacobs WB, Zhang JJ, Moro A, Park JH,
Kushida M, Qiu W, Mills AA, Kim PC. DeltaNp63 plays an anti-apoptotic
role in ventral bladder development. Development. 2006
Dec;133(23):4783-92. Epub 2006 Nov 1. |
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Chiao E, Elazar M, Xing Y, Xiong A, Kmet M, Millan MT,
Glenn JS, Wong WH, Baker J. Isolation and Transcriptional Profiling of
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Crossno JT Jr, Majka SM, Grazia T, Gill RG,
Klemm DJ. Rosiglitazone promotes development of a novel adipocyte
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Dai J, Hall CL, Escara-Wilke J, Mizokami A, Keller JM,
Keller ET. Prostate cancer induces bone metastasis through Wnt-induced
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Datta A, Sinha-Datta U, Dhillon NK, Buch S,
Nicot C. The HTLV-I p30 Interferes with TLR4 Signaling and Modulates the
Release of Pro- and Anti-inflammatory Cytokines from Human Macrophages.
J Biol Chem. 2006 Aug 18;281(33):23414-24. Epub 2006 Jun 19. |
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Demorrow S, Francis H, Gaudio E, Ueno Y, Venter J, Onori
P, Franchitto A, Vaculin B, Vaculin S, Alpini G Anandamide inhibits
cholangiocyte hyperplastic proliferation via activation of thioredoxin
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DeMorrow S, Glaser S, Francis H, Venter J,
Vaculin B, Vaculin S, Alpini G Opposing actions of endocannabinoids on
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Dhillon NK, Peng F, Ransohoff RM, Buch S PDGF
synergistically enhances IFN-gamma-induced expression of CXCL10 in
blood-derived macrophages: implications for HIV dementia. J Immunol.
2007 Sep 1;179(5):2722-30 |
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Dimitrijevic OB, Stamatovic SM, Keep RF,
Andjelkovic AV Absence of the chemokine receptor CCR2 protects against
cerebral ischemia/reperfusion injury in mice. Stroke. 2007
Apr;38(4):1345-53. Epub 2007 Mar 1 |
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Dominguez J, Wu P, Packer CS, Temm C, Kelly
KJ. Lipotoxic and inflammatory phenotypes in rats with uncontrolled
metabolic syndrome and nephropathy. Am J Physiol Renal Physiol. 2007
Sep;293(3):F670-9. Epub 2007 Jun 27 |
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Drew JE, Farquharson AJ, Padidar S, Duthie GG,
Mercer JG, Arthur JR, Morrice PC, Barrera LN. Insulin, leptin, and
adiponectin receptors in colon: regulation relative to differing body
adiposity independent of diet and in response to dimethylhydrazine. Am J
Physiol Gastrointest Liver Physiol. 2007 Oct;293(4):G682-91. Epub 2007
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Emmons J, Townley-Tilson WH, Deleault KM, Skinner SJ,
Gross RH, Whitfield ML, Brooks SA Identification of TTP mRNA targets in
human dendritic cells reveals TTP as a critical regulator of dendritic
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Enshell-Seijffers D, Lindon C, Morgan BA. The serine
protease Corin is a novel modifier of the agouti pathway. Development.
2008 Jan;135(2):217-25. Epub 2007 Dec 5 |
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Fang CH, Li B, James JH, Yahya A, Kadeer N,
Guo X, Xiao C, Supp DM, Kagan RJ, Hasselgren PO, Sheriff S. GSK-3beta
activity is increased in skeletal muscle after burn injury in rats. Am J
Physiol Regul Integr Comp Physiol. 2007 Oct;293(4):R1545-51. Epub 2007
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Fang J, Menon M, Kapelle W, Bogacheva O,
Bogachev O, Houde E, Browne S, Sathyanarayana P, Wojchowski DM EPO
modulation of cell-cycle regulatory genes, and cell division, in primary
bone marrow erythroblasts. Blood. 2007 Oct 1;110(7):2361-70. Epub 2007
Jun 4 |
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Ferron M, Hinoi E, Karsenty G, Ducy P. Osteocalcin
differentially regulates beta cell and adipocyte gene expression and
affects the development of metabolic diseases in wild-type mice. Proc
Natl Acad Sci U S A. 2008 Apr 1;105(13):5266-70. Epub 2008 Mar 24. |
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Forbes EE, Groschwitz K, Abonia JP, Brandt EB, Cohen E,
Blanchard C, Ahrens R, Seidu L, McKenzie A, Strait R, Finkelman FD,
Foster PS, Matthaei KI, Rothenberg ME, Hogan SP IL-9- and mast
cell-mediated intestinal permeability predisposes to oral antigen
hypersensitivity. J Exp Med. 2008 Apr 14;205(4):897-913. Epub 2008 Mar
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Franchi A, Zaret J, Zhang X, Bocca S, Oehninger S.
Expression of immunomodulatory genes and their ligands/receptors during
the window of implantation in human endometrium. Mol Hum Reprod. 2008
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Fujiwara K, Daido S, Yamamoto A, Kobayashi R,
Yokoyama T, Aoki H, Iwado E, Shinojima N, Kondo Y, Kondo S. Pivotal role
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Glaser S, Demorrow S, Francis H, Ueno Y, Gaudio E,
Vaculin S, Venter J, Franchitto A, Onori P, Vaculin B, Marzioni M, Wise
C, Pilanthananond M, Savage J, Pierce L, Mancinelli R, Alpini G.
Progesterone stimulates the proliferation of female and male
cholangiocytes via autocrine/paracrine mechanisms. Am J Physiol
Gastrointest Liver Physiol. 2008 Jul;295(1):G124-G136. Epub 2008 May
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Grigore D, Ojeda NB, Robertson EB, Dawson AS,
Huffman CA, Bourassa EA, Speth RC, Brosnihan KB, Alexander BT. Placental
insufficiency results in temporal alterations in the renin angiotensin
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Guo Y, Mantel C, Hromas RA, Broxmeyer HE. Oct
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Hamill CE, Caudle WM, Richardson JR, Yuan H,
Pennell KD, Greene JG, Miller GW, Traynelis SF. Exacerbation of
dopaminergic terminal damage in a mouse model of Parkinson's disease by
the G-protein-coupled receptor protease-activated receptor 1. Mol
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Hamilton KL, Lin L, Wang Y, Knowlton AA.
Effect of Ovariectomy on Cardiac Gene Expression: Inflammation and
Changes in SOCS Genes Expression Physiol Genomics. 2007 Nov 6; [Epub
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Hirbe AC, Rubin J, Uluçan O, Morgan
EA, Eagleton MC, Prior JL, Piwnica-Worms D, Weilbaecher KN. Disruption
of CXCR4 enhances osteoclastogenesis and tumor growth in bone. Proc Natl
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Hooks JJ, Nagineni CN, Hooper LC, Hayashi K, Detrick B.
IFN-beta provides immuno-protection in the retina by inhibiting ICAM-1
and CXCL9 in retinal pigment epithelial cells J Immunol. 2008 Mar
15;180(6):3789-96 |
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Hsu S, Dickinson DP, Qin H, Lapp C, Lapp D, Borke J,
Walsh DS, Bollag WB, Stoppler H, Yamamoto T, Osaki T, Schuster G
Inhibition of autoantigen expression by (-)-epigallocatechin-3-gallate
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Hu YF, Zhang ZJ, Sieber-Blum M An epidermal
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Jiao J, Wang S, Qiao R, Vivanco I, Watson PA,
Sawyers CL, Wu H. Murine cell lines derived from Pten null prostate
cancer show the critical role of PTEN in hormone refractory prostate
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Jones RA, Campbell CI, Petrik JJ, Moorehead RA
Characterization of a Novel Primary Mammary Tumor Cell Line Reveals that
Cyclin D1 Is Regulated by the Type I Insulin-Like Growth Factor
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Kafienah W, Mistry S, Perry MJ, Politopoulou
G, Hollander AP Pharmacological regulation of adult stem cells:
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retinoic acid receptor Stem Cells. 2007 Oct;25(10):2460-8. Epub 2007 Jul
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Kim J, Jahng WJ, Di Vizio D, Lee JS, Jhaveri
R, Rubin MA, Shisheva A, Freeman MR. The phosphoinositide kinase PIKfyve
mediates epidermal growth factor receptor trafficking to the nucleus.
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Kline ER, Kleinhenz DJ, Liang B, Dikalov S, Guidot DM,
Hart CM, Jones DP, Sutliff RL. Vascular oxidative stress and nitric
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Kreslavsky T, Garbe AI, Krueger A, von Boehmer H T cell
receptor-instructed {alpha}{beta} versus {gamma}{delta} lineage
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Kuznetsov AV, Smigelskaite J, Doblander C, Janakiraman M,
Hermann M, Wurm M, Scheidl SF, Sucher R, Deutschmann A, Troppmair J.
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Larson JE, Cohen JC "Improvement of
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Lee JK, Mathew SO, Vaidya SV, Kumaresan PR,
Mathew PA. CS1 (CRACC, CD319) induces proliferation and autocrine
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Li S, Nikulina K, DeVoss J, Wu AJ, Strauss EC, Anderson
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Li Y, Mezei O, Shay NF. Human and murine
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Li Z, Mahesh SP, Shen de F, Liu B, Siu WO,
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Lian X, Qin Y, Hossain SA, Yang L, White A,
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Lindemann MJ, Hu Z, Benczik M, Liu KD, Gaffen SL
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Linder AE, Ni W, Szasz T, Burnett R, Diaz J, Geddes TJ,
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Liu J, Hamrouni A, Wolowiec D, Coiteux V,
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Low K, Culbertson M, Bradke F, Tessier-Lavigne M,
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Lowry MH, McAllister BP, Jean JC, Brown LS, Hughey RP,
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Megias J, Guillen MI, Bru A, Gomar F, Alcaraz
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Meyer-Siegler KL, Iczkowski KA, Leng L,
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Mezei O, Li Y, Mullen E, Ross-Viola JS, Shay
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Monroe DG, Secreto FJ, Subramaniam M, Getz BJ,
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Motiwala AS, Janagama HK, Paustian ML, Zhu X,
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Murphy TR, Legere HJ 3rd, Katz HR Activation
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Nam JS, Kang MJ, Suchar AM, Shimamura T, Kohn
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Navedo MF, Nieves-Cintron M, Amberg GC, Yuan C,
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Ni W, Fink GD, Watts SW. The
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Niculescu MD, da Costa KA, Fischer LM, Zeisel
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Ojeda NB, Grigore D, Robertson EB, Alexander
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Pandey J, Umphress SM, Kang Y, Angdisen J, Naumova A,
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Paruchuri S, Jiang Y, Feng C, Francis SA, Plutzky J,
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Peyrou M, Hanna PE, Cribb AE. Cisplatin,
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Qin S, Liu T, Kamanna VS, Kashyap ML
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Rajendram R, Saraswathy S, Rao NA.
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Rao NA, Saraswathy S, Wu GS, Katselis GS, Wawrousek EF,
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Reen RK, Dombkowski AA, Kresty LA, Cukovic D,
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Sadun RE, Sachsman SM, Chen X, Christenson
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Sama MA, Mathis DM, Furman JL, Mohmmad Abdul H, Artiushin
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Sathyanarayana P, Menon MP, Bogacheva O,
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Sawiris GP, Becker KG, Elliott EJ, Moulden R,
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Schenke-Layland K, Angelis E, Rhodes KE,
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Schiffer L, Bethunaickan R, Ramanujam M, Huang W,
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Sebastian T, Malik R, Thomas S, Sage J,
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Secchiero P, Corallini F, Rimondi E,
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Seijffers R, Mills CD, Woolf CJ. ATF3
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Shen CH, Ge Q, Talay O, Eisen HN, Garc?-Sastre A, Chen
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Shi T, Duan ZH, Papay R, Pluskota E, Gaivin
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Shukla A, Ho Y, Liu X, Ryscavage A, Glick AB Cripto-1
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Singh PK, Behrens ME, Eggers JP, Cerny RL, Bailey JM,
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Sun HD, Malabunga M, Tonra JR, Direnzo R,
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Sun K, Li M, Sayers TJ, Welniak LA, Murphy WJ.
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Tongers J, Knapp JM, Korf M, Kempf T, Limbourg A,
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Tuo J, Bojanowski CM, Zhou M, Shen D, Ross
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van Hees HW, Li YP, Ottenheijm CA, Jin B, Pigmans CJ,
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Wang Z, Aris VM, Ogburn KD, Soteropoulos P,
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Watanabe K, Bianco C, Strizzi L, Hamada S,
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Watkins SK, Egilmez NK, Suttles J, Stout RD.
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Xian W, Schwertfeger KL, Vargo-Gogola T,
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Yang L, Wang L, Kalfa T, Cancelas JA, Shang
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Zhang Y, Andl T, Yang SH, Teta M, Liu F, Seykora JT,
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Zhou J, Liu M, Zhai Y, Xie W The Anti-Apoptotic Role of
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RT² SYBR Green qPCR Master Mixes
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/ Stratagene: SYBR Green / ROX |
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Fleming AB, Pennings S. Tup1-Ssn6 and Swi-Snf remodelling
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Gregory-Evans CY, Moosajee M, Hodges MD, Mackay DS, Game
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Kim YS, Kang HS, Herbert R, Beak JY, Collins JB, Grissom
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Ma X, Shah Y, Cheung C, Guo GL, Feigenbaum L, Krausz KW,
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Sama MA, Mathis DM, Furman JL, Mohmmad Abdul H, Artiushin
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Secchiero P, Corallini F, Rimondi E, Chiaruttini C, di
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Smed-S?ensen A, Moll M, Cheng TY, Lor?K, Norlin AC,
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Sung B, Pandey MK, Ahn KS, Yi T, Chaturvedi MM, Liu M,
Aggarwal BB Anacardic acid (6-nonadecyl salicylic acid), an inhibitor of
histone acetyltransferase, suppresses expression of nuclear factor-kappaB-regulated
gene products involved in cell survival, proliferation, invasion, and
inflammation through inhibition of the inhibitory subunit of nuclear
factor-kappaBalpha kinase, leading to potentiation of apoptosis Blood.
2008 May 15;111(10):4880-91. Epub 2008 Mar 18 |
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Wang T, Ma X, Krausz KW, Idle JR, Gonzalez FJ. Role of
pregnane X receptor in control of all-trans retinoic acid (ATRA)
metabolism and its potential contribution to ATRA resistance. J
Pharmacol Exp Ther. 2007 Oct 25; [Epub ahead of print] |
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Weaver IC, D'Alessio AC, Brown SE, Hellstrom IC, Dymov S,
Sharma S, Szyf M, Meaney MJ. The transcription factor nerve growth
factor-inducible protein a mediates epigenetic programming: altering
epigenetic marks by immediate-early genes. J Neurosci. 2007 Feb
14;27(7):1756-68. |
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White DL, Saunders VA, Dang P, Engler J, Venables A, Zrim
S, Zannettino A, Lynch K, Manley PW, Hughes T. Most CML patients who
have a suboptimal response to imatinib have low OCT-1 activity: higher
doses of imatinib may overcome the negative impact of low OCT-1
activity. Blood. 2007 Dec 1;110(12):4064-72. Epub 2007 Aug 30 |
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| Bio-Rad:
SYBR Green / Fluorescein |
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Chiao E, Elazar M, Xing Y, Xiong A, Kmet M, Millan MT,
Glenn JS, Wong WH, Baker J. Isolation and Transcriptional Profiling of
Purified Hepatic Cells Derived from Human Embryonic Stem Cells. Stem
Cells. 2008 Jun 5. [Epub ahead of print] |
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Han L, Lee DH, Szab?PE CTCF is the master organizer of
domain-wide allele-specific chromatin at the H19/Igf2 imprinted region.
Mol Cell Biol. 2008 Feb;28(3):1124-35. Epub 2007 Nov 26 |
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L? K, Culbertson M, Bradke F, Tessier-Lavigne M,
Tuszynski MH. Netrin-1 is a novel myelin-associated inhibitor to axon
growth. J Neurosci. 2008 Jan 30;28(5):1099-108 |
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Stark K, Wu ZL, Bartleson CJ, Guengerich FP. mRNA
Distribution and Heterologous Expression of Orphan Cytochrome P450 20A1.
Drug Metab Dispos. 2008 Jun 9. [Epub ahead of print] |
PUBMED |
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Qin S, Liu T, Kamanna VS, Kashyap ML Pioglitazone
stimulates apolipoprotein A-I production without affecting HDL removal
in HepG2 cells: involvement of PPAR-alpha. Arterioscler Thromb Vasc
Biol. 2007 Nov;27(11):2428-34. Epub 2007 Sep 13. |
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| Others:
SYBR Green |
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Brown SE, Szyf M. Epigenetic programming of the rRNA
promoter by MBD3 Mol Cell Biol. 2007 Jul;27(13):4938-52. Epub 2007 Apr
23. |
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Carreras E, Turner S, Paharkova-Vatchkova V, Mao A,
Dascher C, Kovats S. Estradiol acts directly on bone marrow myeloid
progenitors to differentially regulate GM-CSF or Flt3 ligand-mediated
dendritic cell differentiation J Immunol. 2008 Jan
15;180(2):727-38. |
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Emmons J, Townley-Tilson WH, Deleault KM, Skinner SJ,
Gross RH, Whitfield ML, Brooks SA Identification of TTP mRNA targets in
human dendritic cells reveals TTP as a critical regulator of dendritic
cell maturation. RNA. 2008 May;14(5):888-902. Epub 2008 Mar 26. |
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Hernandez Y, Shpak M, Duarte TT, Mendez TL, Maldonado RA,
Roychowdhury S, Rodrigues ML, Das S. Novel role of sphingolipid
synthesis genes in regulating giardial encystation. Infect Immun. 2008
Jul;76(7):2939-49. Epub 2008 Apr 21. |
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Hu W, Mahavadi S, Li F, Murthy KS. Up-Regulation of RGS4
and Down-Regulation of CPI-17 Mediate Inhibition of Colonic Muscle
Contraction by Interleukin-1{beta} Am J Physiol Cell Physiol. 2007 Oct
24; [Epub ahead of print] |
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Kim JS, Bailey MJ, Ho AK, Møller M, Gaildrat P, Klein
DC. Daily rhythm in pineal phosphodiesterase (PDE) activity reflects
adrenergic/3',5'-cyclic adenosine 5'-monophosphate induction of the
PDE4B2 variant. Endocrinology. 2007 Apr;148(4):1475-85. Epub 2007 Jan 4. |
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Kopp JL, Ormsbee BD, Desler M, Rizzino A. Small Increases
in the Level of Sox2 Trigger the Differentiation of Mouse Embryonic Stem
Cells. Stem Cells. 2008 Jan 31 [Epub ahead of print] |
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Kopp JL, Wilder PJ, Desler M, Kinarsky L, Rizzino A.
Different domains of the transcription factor ELF3 are required in a
promoter-specific manner and multiple domains control its binding to
DNA. J Biol Chem. 2007 Feb 2;282(5):3027-41. Epub 2006 Dec 5. |
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Peyrou M, Hanna PE, Cribb AE. Cisplatin, gentamicin, and
p-aminophenol induce markers of endoplasmic reticulum stress in the rat
kidneys. Toxicol Sci. 2007 Sep;99(1):346-53. Epub 2007 Jun 12. |
PUBMED |
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Robert R, Carlile GW, Pavel C, Liu N, Anjos SM, Liao J,
Luo Y, Zhang D, Thomas DY, Hanrahan JW. Structural analogue of
sildenafil identified as a novel corrector of the F508del-CFTR
trafficking defect. Mol Pharmacol. 2007 Nov 1; [Epub ahead of print |
PUBMED |
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Seijffers R, Mills CD, Woolf CJ. ATF3 increases the
intrinsic growth state of DRG neurons to enhance peripheral nerve
regeneration. J Neurosci. 2007 Jul 25;27(30):7911-20. |
PUBMED |
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Soundararajan R, Wishart AD, Rupasinghe HP,
Arcellana-Panlilio M, Nelson CM, Mayne M, Robertson GS.
Quercetin-3-glucoside protects neuroblastoma (SH-SY5Y) cells in vitro
against oxidative damage by inducing SREBP-2 mediated cholesterol
biosynthesis. J Biol Chem. 2007 Nov 20 [Epub ahead of print]. |
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Stepanova V, Lebedeva T, Kuo A, Yarovoi S, Tkachuk S,
Zaitsev S, Bdeir K, Dumler I, Marks MS, Parfyonova Y, Tkachuk VA, Higazi
AA, Cines DB. Nuclear translocation of urokinase-type plasminogen
activator. Blood. 2008 Jul 1;112(1):100-10. Epub 2008 Mar 12. |
PUBMED |
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Wang T, Ma X, Krausz KW, Idle JR, Gonzalez FJ. Role of
pregnane X receptor in control of all-trans retinoic acid (ATRA)
metabolism and its potential contribution to ATRA resistance. J
Pharmacol Exp Ther. 2008 Feb;324(2):674-84. Epub 2007 Oct 25. |
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Wu S, Peng J, Duncan MR, Kasisomayajula K, Grotendorst G,
Bancalari E ALK-5 Mediates Endogenous and TGF-{beta}1-induced Expression
of CTGF in Embryonic Lung. Am J Respir Cell Mol Biol. 2006 Dec 29; [Epub
ahead of print]. |
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Yan Y, Black CP, Cao PT, Haferbier JL, Kolb RH, Spieker
RS, Ristow AM, Cowan KH. Gamma-irradiation-induced DNA damage checkpoint
activation involves feedback regulation between extracellular
signal-regulated kinase 1/2 and BRCA1. Cancer Res. 2008 Jul
1;68(13):5113-21. |
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You M, Liang X, Ajmo JM, Ness GC Involvement of mammalian
sirtuin 1 in the action of ethanol in the liver. Am J Physiol
Gastrointest Liver Physiol. 2008 Apr;294(4):G892-8. Epub 2008 Jan
31 |
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Zhang MY, Wu X, Lee AJ, Jin W, Chang M, Wright A,
Imaizumi T, Sun SC. Regulation of I{kappa}B Kinase-related Kinases and
Antiviral Responses by Tumor Suppressor CYLD. J Biol Chem. 2008 Jul
4;283(27):18621-6. Epub 2008 May 8. |
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Zolfaghari R, Cifelli CJ, Lieu SO, Chen Q, Li NQ, Ross
AC. Lipopolysaccharide opposes the induction of CYP26A1 and CYP26B1 gene
expression by retinoic acid in the rat liver in vivo. Am J Physiol
Gastrointest Liver Physiol. 2007 Apr;292(4):G1029-36. Epub 2006 Dec 21 |
PUBMED |
BACK TO TOP
Oligo GEArray DNA Microarrays
| Angiogenesis |
|
Lazar AJ, Das P, Tuvin D, Korchin B, Zhu Q, Jin Z,
Warneke CL, Zhang PS, Hernandez V, Lopez-Terrada D, Pisters PW, Pollock
RE, Lev D Angiogenesis-promoting gene patterns in alveolar soft part
sarcoma Clin Cancer Res. 2007 Dec 15;13(24):7314-21 |
PUBMED |
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| Apoptosis |
|
Azuma T, Yao S, Zhu G, Flies AS, Flies SJ, Chen L. B7-H1
is a ubiquitous antiapoptotic receptor on cancer cells. Blood. 2008 Apr
1;111(7):3635-43. Epub 2008 Jan 25. |
PUBMED |
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Leng Y, Chuang DM. Endogenous alpha-synuclein
is induced by valproic acid through histone deacetylase inhibition and
participates in neuroprotection against glutamate-induced excitotoxicity.
J Neurosci. 2006 Jul 12;26(28):7502-12. |
PUBMED |
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Low GK, Fok ED, Ting AP, Hande MP. Oxidative damage
induced genotoxic effects in human fibroblasts from Xeroderma
Pigmentosum group A patients. Int J Biochem Cell Biol. 2008 May 21. [Epub
ahead of print] |
PUBMED |
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Nefedova Y, Sullivan DM, Bolick SC, Dalton WS,
Gabrilovich DI Inhibition of Notch signaling induces apoptosis of
myeloma cells and enhances sensitivity to chemotherapy. Blood. 2008 Feb
15;111(4):2220-9. Epub 2007 Nov 26. |
PUBMED |
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Pandey J, Umphress SM, Kang Y, Angdisen J, Naumova A,
Mercer KL, Jacks T, Jakowlew SB Modulation of tumor induction and
progression of oncogenic K-ras-positive tumors in the presence of TGF- 1
haploinsufficiency. Carcinogenesis. 2007 Dec;28(12):2589-96. Epub 2007
Aug 8 |
PUBMED |
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Staiger K, Staiger H, Weigert C, Haas C,
Haring HU, Kellerer M. Saturated, but not unsaturated, fatty acids
induce apoptosis of human coronary artery endothelial cells via nuclear
factor-kappaB activation. Diabetes. 2006 Nov;55(11):3121-6. |
PUBMED |
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Yan H, Frost P, Shi Y, Hoang B, Sharma S,
Fisher M, Gera J, Lichtenstein A. Mechanism by which mammalian target of
rapamycin inhibitors sensitize multiple myeloma cells to dexamethasone-induced
apoptosis Cancer Res. 2006 Feb 15;66(4):2305-13. |
PUBMED |
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Zhang M, Marshall B, Atherton SS. Murine cytomegalovirus
infection and apoptosis in organotypic retinal cultures Invest
Ophthalmol Vis Sci. 2008 Jan;49(1):295-303 |
PUBMED |
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Zhou J, Liu M, Zhai Y, Xie W The Anti-Apoptotic Role of
Pregnane X Receptor in Human Colon Cancer Cells Mol Endocrinol. 2007 Dec
20 [Epub ahead of print] |
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| Atherosclerosis |
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Harvey EJ, Li N, Ramji DP. Critical role for
casein kinase 2 and phosphoinositide-3-kinase in the
interferon-gamma-induced expression of monocyte chemoattractant
protein-1 and other key genes implicated in atherosclerosis.
Arterioscler Thromb Vasc Biol. 2007 Apr;27(4):806-12. Epub 2007 Jan 25 |
PUBMED |
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| Cancer |
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Bryan BA, Dyson OF, Akula SM. Identifying
cellular genes crucial for the reactivation of Kaposi's
sarcoma-associated herpesvirus latency. J Gen Virol. 2006 Mar;87(Pt
3):519-29. |
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Frommer KW, Reichenmiller K, Schutt BS,
Hoeflich A, Ranke MB, Dodt G, Elmlinger MW. IGF-independent effects of
IGFBP-2 on the human breast cancer cell line Hs578T. J Mol Endocrinol.
2006 Aug;37(1):13-23. |
PUBMED |
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| Cancer
PathwayFinder |
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Li H, Fan X, Kovi RC, Jo Y, Moquin B, Konz R,
Stoicov C, Kurt-Jones E, Grossman SR, Lyle S, Rogers AB, Montrose M,
Houghton J. Spontaneous expression of embryonic factors and p53 point
mutations in aged mesenchymal stem cells: a model of age-related
tumorigenesis in mice. Cancer Res. 2007 Nov 15;67(22):10889-98. |
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Shao J, Washington MK, Saxena R, Sheng H Heterozygous
disruption of the PTEN promotes intestinal neoplasia in APCmin/+ mouse:
roles of osteopontin. Carcinogenesis. 2007 Dec;28(12):2476-83. Epub 2007
Aug 11 |
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| Cell
Cycle |
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Jang SI, Lee EJ, Hart PS, Ramaswami M, Pallos
D, Hart TC Germ line gain of function with SOS1 mutation in hereditary
gingival fibromatosis. J Biol Chem. 2007 Jul 13;282(28):20245-55. Epub
2007 May 17. |
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Klokk TI, Kilander A, Xi Z, Waehre H, Risberg
B, Danielsen HE, Saatcioglu F. Kallikrein 4 is a proliferative factor
that is overexpressed in prostate cancer. Cancer Res. 2007 Jun
1;67(11):5221-30 |
PUBMED |
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Pandey J, Umphress SM, Kang Y, Angdisen J, Naumova A,
Mercer KL, Jacks T, Jakowlew SB Modulation of tumor induction and
progression of oncogenic K-ras-positive tumors in the presence of TGF- 1
haploinsufficiency. Carcinogenesis. 2007 Dec;28(12):2589-96. Epub 2007
Aug 8 |
PUBMED |
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Rubinek T, Chesnokova V, Wolf I, Wawrowsky K,
Vlotides G, Melmed S Discordant proliferation and differentiation in
pituitary tumor-transforming gene-null bone marrow stem cells. Am J
Physiol Cell Physiol. 2007 Sep;293(3):C1082-92. Epub 2007 Jul 11 |
PUBMED |
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| Cell
Surface Markers |
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Wang L, O'Leary H, Fortney J, Gibson LF. Ph+/VE-cadherin+
identifies a stem cell like population of acute lymphoblastic leukemia
sustained by bone marrow niche cells. Blood. 2007 Nov 1;110(9):3334-44.
Epub 2007 Jul 16. |
PUBMED |
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| Chemokines
& Receptors |
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Fischer J, West J, Agochukwu N, Suire C,
Hale-Donze H. Induction of host chemotactic response by Encephalitozoon
spp Infect Immun. 2007 Apr;75(4):1619-25. Epub 2006 Dec 18. |
PUBMED |
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Schenk S, Mal N, Finan A, Zhang M, Kiedrowski
M, Popovic Z, McCarthy PM, Penn MS. Monocyte chemotactic protein-3 is a
myocardial mesenchymal stem cell homing factor. Stem Cells. 2007
Jan;25(1):245-51. Epub 2006 Oct 19. |
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Sinha I, Cho BS, Roelofs KJ, Stanley JC,
Henke PK, Upchurch GR Jr Female gender attenuates cytokine and chemokine
expression and leukocyte recruitment in experimental rodent abdominal
aortic aneurysms. Ann N Y Acad Sci. 2006 Nov;1085:367-79 |
PUBMED |
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Son DS, Roby KF. Interleukin-1alpha-induced
chemokines in mouse granulosa cells: impact on keratinocyte
chemoattractant chemokine, a CXC subfamily. Mol Endocrinol. 2006
Nov;20(11):2999-3013. Epub 2006 Jul 6. |
PUBMED |
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| Common
Cytokines |
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Korshunov VA, Nikonenko TA, Tkachuk VA,
Brooks A, Berk BC Interleukin-18 and macrophage migration inhibitory
factor are associated with increased carotid intima-media thickening
Arterioscler Thromb Vasc Biol. 2006 Feb;26(2):295-300. Epub 2005 Nov 17 |
PUBMED |
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Lee JK, Mathew SO, Vaidya SV, Kumaresan PR,
Mathew PA. CS1 (CRACC, CD319) induces proliferation and autocrine
cytokine expression on human B lymphocytes. J Immunol. 2007 Oct
1;179(7):4672-8. |
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Ou R, Zhang M, Huang L, Flavell RA, Koni PA, Moskophidis
D. Regulation of immune response and inflammatory reactions against
viral infection by VCAM-1. J Virol. 2008 Mar;82(6):2952-65. Epub 2008
Jan 23 |
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Sinha I, Cho BS, Roelofs KJ, Stanley JC,
Henke PK, Upchurch GR Jr Female gender attenuates cytokine and chemokine
expression and leukocyte recruitment in experimental rodent abdominal
aortic aneurysms. Ann N Y Acad Sci. 2006 Nov;1085:367-79 |
PUBMED |
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| Custom |
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Djamali A. Oxidative stress as a common
pathway to chronic tubulointerstitial injury in kidney allografts. Am J
Physiol Renal Physiol. 2007 Aug;293(2):F445-55. Epub 2007 Apr 25. |
PUBMED |
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Huang HS, Matevossian A, Whittle C, Kim SY,
Schumacher A, Baker SP, Akbarian S Prefrontal dysfunction in
schizophrenia involves mixed-lineage leukemia 1-regulated histone
methylation at GABAergic gene promoters. J Neurosci. 2007 Oct
17;27(42):11254-62. |
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| Dendritic
& Antigen Presenting Cells |
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Luo Y, Schwartz C, Shin S, Zeng X, Chen N,
Wang Y, Yu X, Rao MS. A focused microarray to assess dopaminergic and
glial cell differentiation from fetal tissue or embryonic stem cells
Stem Cells. 2006 Apr;24(4):865-75. Epub 2005 Dec 15. |
PUBMED |
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| DNA
Damage Signaling |
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Chesnokova V, Zonis S, Rubinek T, Yu R, Ben-Shlomo
A, Kovacs K, Wawrowsky K, Melmed S. Senescence mediates pituitary
hypoplasia and restrains pituitary tumor growth. Cancer Res. 2007 Nov
1;67(21):10564-72. |
PUBMED |
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| Extracellular
Matrix & Adhesion Molecules |
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Hannan NJ, Salamonsen LA. CX3CL1 and CCL14 Regulate
Extracellular Matrix and Adhesion Molecules in the Trophoblast:
Potential Roles in Human Embryo Implantation. Biol Reprod. 2008
Jul;79(1):58-65. Epub 2008 Mar 26. |
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Khan ZA, Melero-Martin JM, Wu X, Paruchuri S, Boscolo E,
Mulliken JB, Bischoff J. Endothelial progenitor cells from infantile
hemangioma and umbilical cord blood display unique cellular responses to
endostatin. Blood. 2006 Aug 1;108(3):915-21. |
PUBMED |
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Romain D, Sylvie BP, Johanna L, Alain M, Aurelie D,
Fran?is-Xavier M, William H, Irfan R, Frank A. Laboratoire de
Biochimie, Universit?de REIMS Champagne-Ardenne, CNRS UMR-6237, 51095
REIMS Cedex, France Biochim Biophys Acta. 2008 Jun 13. [Epub ahead of
print] |
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Taniwaki K, Fukamachi H, Komori K, Ohtake Y, Nonaka T,
Sakamoto T, Shiomi T, Okada Y, Itoh T, Itohara S, Seiki M, Yana I.
Stroma-derived matrix metalloproteinase (MMP)-2 promotes membrane type
1-MMP-dependent tumor growth in mice. Cancer Res. 2007 May
1;67(9):4311-9 |
PUBMED |
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| Hypoxia
Signaling |
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Kubo M, Li TS, Suzuki R, Shirasawa B, Morikage N, Ohshima
M, Qin SL, Hamano K Hypoxic preconditioning increases survival and
angiogenic potency of peripheral blood mononuclear cells via oxidative
stress resistance Am J Physiol Heart Circ Physiol. 2008
Feb;294(2):H590-5. Epub 2007 Dec 21 |
PUBMED |
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| Inflammatory
Cytokines & Receptors |
|
Aravalli RN, Hu S, Rowen TN, Palmquist JM,
Lokensgard JR. Cutting edge: TLR2-mediated proinflammatory cytokine and
chemokine production by microglial cells in response to herpes simplex
virus J Immunol. 2005 Oct 1;175(7):4189-93. |
PUBMED |
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Ganta CK, Helwig BG, Blecha F, Ganta RR,
Cober R, Parimi S, Musch TI, Fels RJ, Kenney MJ.
"Hypothermia-enhanced Splenic Cytokine Gene Expression is
Independent of the Sympathetic Nervous System. Am J Physiol Regul Integr
Comp Physiol. 2006 Feb 9; [Epub ahead of print] |
PUBMED |
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Lee JH, Kim M, Im YS, Choi W, Byeon SH, Lee HK NFAT5
induction and its role in hyperosmolar stressed human limbal epithelial
cells. Invest Ophthalmol Vis Sci. 2008 May;49(5):1827-35 |
PUBMED |
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Rupprecht TA, Angele B, Klein M, Heesemann J,
Pfister HW, Botto M, Koedel U. Complement C1q and C3 are critical for
the innate immune response to Streptococcus pneumoniae in the central
nervous system. J Immunol. 2007 Feb 1;178(3):1861-9. |
PUBMED |
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Vera PL, Wang X, Meyer-Siegler KL. Upregulation of
macrophage migration inhibitory factor (MIF) and CD74, receptor for MIF,
in rat bladder during persistent cyclophosphamide-induced inflammation
Exp Biol Med (Maywood). 2008 May;233(5):620-6. Epub 2008 Mar 28. |
PUBMED |
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Nacu N, Luzina IG, Highsmith K, Lockatell V, Pochetuhen
K, Cooper ZA, Gillmeister MP, Todd NW, Atamas SP Macrophages produce TGF-beta-induced
(beta-ig-h3) following ingestion of apoptotic cells and regulate MMP14
levels and collagen turnover in fibroblasts J Immunol. 2008 Apr
1;180(7):5036-44 |
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Bald? A, Gomes AV, Ping P, Edwards PA. Loss of ABCG1
Results in Chronic Pulmonary Inflammation. J Immunol. 2008 Mar
1;180(5):3560-8 |
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| Insulin
Signaling |
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Fulzele K, DiGirolamo DJ, Liu Z, Xu J,
Messina JL, Clemens TL. Disruption of the insulin-like growth factor
type 1 receptor in osteoblasts enhances insulin signaling and action. J
Biol Chem. 2007 Aug 31;282(35):25649-58. Epub 2007 Jun 6. |
PUBMED |
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| JAK
/ STAT Signaling |
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Liby K, Voong N, Williams CR, Risingsong R,
Royce DB, Honda T, Gribble GW, Sporn MB, Letterio JJ. The synthetic
triterpenoid CDDO-Imidazolide suppresses STAT phosphorylation and
induces apoptosis in myeloma and lung cancer cells. Clin Cancer Res.
2006 Jul 15;12(14 Pt 1):4288-93. |
PUBMED |
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Vargas-Inchaustegui DA, Xin L, Soong L Leishmania
braziliensis Infection Induces Dendritic Cell Activation, ISG15
Transcription, and the Generation of Protective Immune Responses. J
Immunol. 2008 Jun 1;180(11):7537-45. |
PUBMED |
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| Neurogenesis
& Neural Stem Cells |
|
Greco SJ, Rameshwar P Enhancing effect of
IL-1alpha on neurogenesis from adult human mesenchymal stem cells:
implication for inflammatory mediators in regenerative medicine. J
Immunol. 2007 Sep 1;179(5):3342-50 |
PUBMED |
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| NFκB Signaling |
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de Oliveira-Marques V, Cyrne L, Marinho HS,
Antunes F A Quantitative Study of NF-{kappa}B Activation by H2O2:
Relevance in Inflammation and Synergy with TNF-{alpha}. J Immunol. 2007
Mar 15;178(6):3893-902. |
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Emdad L, Sarkar D, Su ZZ, Randolph A,
Boukerche H, Valerie K, Fisher PB Activation of the nuclear factor
kappaB pathway by astrocyte elevated gene-1: implications for tumor
progression and metastasis Cancer Res. 2006 Feb 1;66(3):1509-16. |
PUBMED |
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Liu B, Li Z, Mahesh SP, Pantanelli S, Hwang FS, Siu WO,
Nussenblatt RB. Glucocorticoid-induced Tumor Necrosis Factor Receptor
Negatively Regulates Activation of Human Primary Natural Killer (NK)
Cells by Blocking Proliferative Signals and Increasing NK Cell
Apoptosis. J Biol Chem. 2008 Mar 28;283(13):8202-10. Epub 2008 Jan
29 |
PUBMED |
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| Notch
Signaling |
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Wang L, O'Leary H, Fortney J, Gibson LF. Ph+/VE-cadherin+
identifies a stem cell like population of acute lymphoblastic leukemia
sustained by bone marrow niche cells. Blood. 2007 Nov 1;110(9):3334-44.
Epub 2007 Jul 16. |
PUBMED |
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| Osteogenesis |
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Surmann-Schmitt C, Dietz U, Kireva T, Adam N, Park J,
Tagariello A, Onnerfjord P, Heineg?d D, Schl?zer-Schrehardt U,
Deutzmann R, von der Mark K, Stock M. Ucma, a Novel Secreted
Cartilage-specific Protein with Implications in Osteogenesis J Biol
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Transduction PathwayFinder |
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Kapoor R, Sheng JJ. Transfection of human
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Mirotsou M, Zhang Z, Deb A, Zhang L, Gnecchi
M, Noiseux N, Mu H, Pachori A, Dzau V. Secreted frizzled related protein
2 (Sfrp2) is the key Akt-mesenchymal stem cell-released paracrine factor
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| Stem
Cell |
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Wang L, O'Leary H, Fortney J, Gibson LF. Ph+/VE-cadherin+
identifies a stem cell like population of acute lymphoblastic leukemia
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| TGFβ / BMP Signaling |
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Kato M, Zhang J, Wang M, Lanting L, Yuan H,
Rossi JJ, Natarajan R. MicroRNA-192 in diabetic kidney glomeruli and its
function in TGF-beta-induced collagen expression via inhibition of E-box
repressors. Proc Natl Acad Sci U S A. 2007 Feb 27;104(9):3432-7. Epub
2007 Feb 20. |
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Yamashita M, Otsuka F, Mukai T, Otani H, Inagaki K,
Miyoshi T, Goto J, Yamamura M, Makino H Simvastatin antagonizes tumor
necrosis factor-alpha inhibition of bone morphogenetic
proteins-2-induced osteoblast differentiation by regulating Smad
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& Drug Resistance |
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Zhang L, Hannay JA, Liu J, Das P, Zhan M,
Nguyen T, Hicklin DJ, Yu D, Pollock RE, Lev D. Vascular endothelial
growth factor overexpression by soft tissue sarcoma cells: implications
for tumor growth, metastasis, and chemoresistance. Cancer Res. 2006 Sep
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Metastasis |
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Li H, Fan X, Kovi RC, Jo Y, Moquin B, Konz R,
Stoicov C, Kurt-Jones E, Grossman SR, Lyle S, Rogers AB, Montrose M,
Houghton J. Spontaneous expression of embryonic factors and p53 point
mutations in aged mesenchymal stem cells: a model of age-related
tumorigenesis in mice. Cancer Res. 2007 Nov 15;67(22):10889-98. |
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| WNT
Signaling |
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Baksh D, Yao R, Tuan RS. Comparison of
proliferative and multilineage differentiation potential of human
mesenchymal stem cells derived from umbilical cord and bone marrow. Stem
Cells. 2007 Jun;25(6):1384-92. Epub 2007 Mar 1. |
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Giuliani N, Morandi F, Tagliaferri S,
Lazzaretti M, Donofrio G, Bonomini S, Sala R, Mangoni M, Rizzoli V.
Production of Wnt inhibitors by myeloma cells: potential effects on
canonical Wnt pathway in the bone microenvironment. Cancer Res. 2007 Aug
15;67(16):7665-74 |
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Liu Z, Habener JF. Glucagon-like Peptide-1 Activation of
TCF7L2-dependent Wnt Signaling Enhances Pancreatic Beta Cell
Proliferation. J Biol Chem. 2008 Mar 28;283(13):8723-35. Epub 2008 Jan
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Ortega P, Mor? A, de Juan C, Fr?s C, Hern?dez S,
L?ez-Asenjo JA, S?chez-Pernaute A, Torres A, Iniesta P, Benito M.
Differential Wnt pathway gene expression and E-cadherin truncation in
sporadic colorectal cancers with and without microsatellite instability.
Clin Cancer Res. 2008 Feb 15;14(4):995-1001 |
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Wang L, O'Leary H, Fortney J, Gibson LF. Ph+/VE-cadherin+
identifies a stem cell like population of acute lymphoblastic leukemia
sustained by bone marrow niche cells. Blood. 2007 Nov 1;110(9):3334-44.
Epub 2007 Jul 16 |
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Cantiani L, Manara MC, Zucchini C, De Sanctis
P, Zuntini M, Valvassori L, Serra M, Olivero M, Di Renzo MF, Colombo MP,
Picci P, Scotlandi K. Caveolin-1 reduces osteosarcoma metastases by
inhibiting c-Src activity and met signaling. Cancer Res. 2007 Aug
15;67(16):7675-85. |
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Choudhari SR, Khan MA, Harris G, Picker D,
Jacob GS, Block T, Shailubhai K. Deactivation of Akt and STAT3 signaling
promotes apoptosis, inhibits proliferation, and enhances the sensitivity
of hepatocellular carcinoma cells to an anticancer agent, Atiprimod. Mol
Cancer Ther. 2007 Jan;6(1):112-21. |
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Koshkin V, Dai FF, Robson-Doucette CA, Chan CB, Wheeler
MB Limited Mitochondrial Permeabilization Is an Early Manifestation of
Palmitate-induced Lipotoxicity in Pancreatic {beta}-Cells J Biol Chem.
2008 Mar 21;283(12):7936-48. Epub 2007 Dec 26 |
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Singla DK, Singla RD, McDonald DE. Factors Released
from Embryonic Stem Cells inhibit Apoptosis in H9c2 cells through
P1-3kinase/Akt but not ERK pathway. Am J Physiol Heart Circ Physiol.
2008 Jun 13. [Epub ahead of print] |
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Xia S, Forman LW, Faller DV. Protein kinase C
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| ERBB2 |
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Park JM, Terabe M, Steel JC, Forni G, Sakai Y, Morris
JC, Berzofsky JA. Therapy of advanced established murine breast cancer
with a recombinant adenoviral ErbB-2/neu vaccine Cancer Res. 2008 Mar
15;68(6):1979-87 |
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| ERK |
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Kidd M, Modlin IM, Eick GN, Camp RL, Mane SM
Role of CCN2/CTGF in the proliferation of Mastomys enterochromaffin-like
cells and gastric carcinoid development. Am J Physiol Gastrointest Liver
Physiol. 2007 Jan;292(1):G191-200. Epub 2006 Aug 31. |
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Kidd M, Modlin IM, Gustafsson BI, Drozdov I, Hauso O,
Pfragner R. The luminal regulation of normal and neoplastic human EC
cell serotonin release is mediated by bile salts, amines, tastants and
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Lirk P, Haller I, Colvin HP, Lang L, Tomaselli B,
Klimaschewski L, Gerner P In vitro, inhibition of mitogen-activated
protein kinase pathways protects against bupivacaine- and ropivacaine-induced
neurotoxicity Anesth Analg. 2008 May;106(5):1456-64, table of
contents |
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Perl M, Chung CS, Perl U, Lomas-Neira J, de
Paepe M, Cioffi WG, Ayala A Fas-induced pulmonary apoptosis and
inflammation during indirect acute lung injury. Am J Respir Crit Care
Med. 2007 Sep 15;176(6):591-601. Epub 2007 Jun 28 |
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Singla DK, Singla RD, McDonald DE. Factors Released
from Embryonic Stem Cells inhibit Apoptosis in H9c2 cells through
P1-3kinase/Akt but not ERK pathway. Am J Physiol Heart Circ Physiol.
2008 Jun 13. [Epub ahead of print] |
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Yan Z, Zou H, Tian F, Grandis JR, Mixson AJ, Lu PY, Li
LY. Human rhomboid family-1 gene silencing causes apoptosis or
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| IkBa |
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Kanda N, Watanabe S. Prolactin enhances
interferon-gamma-induced production of CXC ligand 9 (CXCL9), CXCL10, and
CXCL11 in human keratinocytes. Endocrinology. 2007 May;148(5):2317-25.
Epub 2007 Jan 25. |
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Kanda N, Watanabe S. Histamine enhances the
production of human {beta}-defensin-2 in human keratinocytes Am J
Physiol Cell Physiol. 2007 Oct 10; [Epub ahead of print] |
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| JNK |
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Holley SL, Fryer AA, Haycock JW, Grubb SE,
Strange RC, Hoban PR. Differential effects of glutathione S-transferase
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Carcinogenesis. 2007 Nov;28(11):2268-73. Epub 2007 Jun 8. |
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Lirk P, Haller I, Colvin HP, Lang L, Tomaselli B,
Klimaschewski L, Gerner P In vitro, inhibition of mitogen-activated
protein kinase pathways protects against bupivacaine- and ropivacaine-induced
neurotoxicity Anesth Analg. 2008 May;106(5):1456-64, table of
contents |
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Uddin MN, Horvat D, Glaser SS, Mitchell BM, Puschett JB.
Examination of the cellular mechanisms by which marinobufagenin
inhibits cytotrophoblast function. J Biol Chem. 2008 Jun
27;283(26):17946-53. Epub 2008 Apr 23. |
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| NFkB
p65 |
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Kanda N, Watanabe S. Prolactin enhances
interferon-gamma-induced production of CXC ligand 9 (CXCL9), CXCL10, and
CXCL11 in human keratinocytes. Endocrinology. 2007 May;148(5):2317-25.
Epub 2007 Jan 25. |
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Naderi A, Teschendorff AE, Beigel J, Cariati
M, Ellis IO, Brenton JD, Caldas C. BEX2 is overexpressed in a subset of
primary breast cancers and mediates nerve growth factor/nuclear factor-kappaB
inhibition of apoptosis in breast cancer cell lines. Cancer Res. 2007
Jul 15;67(14):6725-36. |
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| p38 |
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Kanda N, Watanabe S. Prolactin enhances
interferon-gamma-induced production of CXC ligand 9 (CXCL9), CXCL10, and
CXCL11 in human keratinocytes. Endocrinology. 2007 May;148(5):2317-25.
Epub 2007 Jan 25. |
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Uddin MN, Horvat D, Glaser SS, Mitchell BM, Puschett JB.
Examination of the cellular mechanisms by which marinobufagenin
inhibits cytotrophoblast function. J Biol Chem. 2008 Jun
27;283(26):17946-53. Epub 2008 Apr 23. |
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| SRC |
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Cantiani L, Manara MC, Zucchini C, De Sanctis
P, Zuntini M, Valvassori L, Serra M, Olivero M, Di Renzo MF, Colombo MP,
Picci P, Scotlandi K. Caveolin-1 reduces osteosarcoma metastases by
inhibiting c-Src activity and met signaling. Cancer Res. 2007 Aug
15;67(16):7675-85. |
PUBMED |
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Gong P, Angelini DJ, Yang S, Xia G, Cross AS, Mann D,
Bannerman DD, Vogel SN, Goldblum SE TLR4 Signaling Is Coupled to SRC
Family Kinase Activation, Tyrosine Phosphorylation of Zonula Adherens
Proteins, and Opening of the Paracellular Pathway in Human Lung
Microvascular Endothelia J Biol Chem. 2008 May 9;283(19):13437-49.
Epub 2008 Mar 7 |
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Uddin MN, Horvat D, Glaser SS, Mitchell BM, Puschett JB.
Examination of the cellular mechanisms by which marinobufagenin
inhibits cytotrophoblast function. J Biol Chem. 2008 Jun
27;283(26):17946-53. Epub 2008 Apr 23. |
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| STAT3 |
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Choudhari SR, Khan MA, Harris G, Picker D,
Jacob GS, Block T, Shailubhai K. Deactivation of Akt and STAT3 signaling
promotes apoptosis, inhibits proliferation, and enhances the sensitivity
of hepatocellular carcinoma cells to an anticancer agent, Atiprimod. Mol
Cancer Ther. 2007 Jan;6(1):112-21. |
PUBMED |
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CASE Inhibitors
| ERK |
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Kroening PR, Barnes TW, Pease L, Limper A, Kita H,
Vassallo R. Cigarette Smoke-Induced Oxidative Stress Suppresses
Generation of Dendritic Cell IL-12 and IL-23 through ERK-Dependent
Pathways. J Immunol. 2008 Jul 15;181(2):1536-47. |
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| JNK |
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Addison WN, Azari F, S?ensen ES, Kaartinen MT, McKee
MD. Pyrophosphate inhibits mineralization of osteoblast cultures by
binding to mineral, up-regulating osteopontin, and inhibiting alkaline
phosphatase activity. J Biol Chem. 2007 May 25;282(21):15872-83. Epub
2007 Mar 23. |
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| p38 |
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Kroening PR, Barnes TW, Pease L, Limper A, Kita H,
Vassallo R. Cigarette Smoke-Induced Oxidative Stress Suppresses
Generation of Dendritic Cell IL-12 and IL-23 through ERK-Dependent
Pathways. J Immunol. 2008 Jul 15;181(2):1536-47. |
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Hamidi SA, Prabhakar S, Said SI. Enhancement of pulmonary
vascular remodelling and inflammatory genes with VIP gene deletion. Eur
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Melnick M, Mocarski ES, Abichaker G, Huang J, Jaskoll T.
Cytomegalovirus-induced embryopathology: mouse submandibular salivary
gland epithelial-mesenchymal ontogeny as a model. BMC Dev Biol. 2006 Sep
7;6:42. |
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Piechocki MP, Yoo GH, Dibbley SK, Lonardo F. Breast
cancer expressing the activated HER2/neu is sensitive to gefitinib in
vitro and in vivo and acquires resistance through a novel point mutation
in the HER2/neu. Cancer Res. 2007 Jul 15;67(14):6825-43 |
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Pinkerton MN, Wescott DC, Gaffey BJ, Beggs KT, Milne TJ,
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express multiple osteotropic cytokines and growth factors, several of
which are responsive to mechanical deformation. J Periodontal Res. 2007
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Raeder S, Utheim TP, Utheim OA, Nicolaissen B, Roald B,
Cai Y, Haug K, Kvalheim A, Messelt EB, Drolsum L, Reed JC, Lyberg T.
Effects of organ culture and Optisol-GS storage on structural integrity,
phenotypes, and apoptosis in cultured corneal epithelium. Invest
Ophthalmol Vis Sci. 2007 Dec;48(12):5484-93. |
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Tilton JC, Manion MM, Luskin MR, Johnson AJ, Patamawenu
AA, Hallahan CW, Cogliano-Shutta NA, Mican JM, Davey RT Jr, Kottilil S,
Lifson JD, Metcalf JA, Lempicki RA, Connors M. Human immunodeficiency
virus viremia induces plasmacytoid dendritic cell activation in vivo and
diminished alpha interferon production in vitro. J Virol. 2008
Apr;82(8):3997-4006. Epub 2008 Feb 6 |
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Wescott DC, Pinkerton MN, Gaffey BJ, Beggs KT, Milne TJ,
Meikle MC. Osteogenic gene expression by human periodontal ligament
cells under cyclic tension. J Dent Res. 2007 Dec;86(12):1212-6. |
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Zhang Y, Woodruff M, Zhang Y, Miao J, Hanley G, Stuart C,
Zeng X, Prabhakar S, Moorman J, Zhao B, Yin D. Toll-like receptor 4
mediates chronic restraint stress-induced immune suppression. J
Neuroimmunol. 2008 Jan 11 [Epub ahead of print] |
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ChampionChIP Chromatin Immunoprecipitation qPCR
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Subbaramaiah K, Hudis C, Chang SH, Hla T, Dannenberg AJ.
EP2 and EP4 Receptors Regulate Aromatase Expression in Human Adipocytes
and Breast Cancer Cells: EVIDENCE OF A BRCA1 AND p300 EXCHANGE. J Biol
Chem. 2008 Feb 8;283(6):3433-44. Epub 2007 Dec 14. |
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ELISArray Kits
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Guo X, Hiroko, Kitmura T, Taketo M, Oshima M. Stromal
fibroblasts activated by tumor cells promote angiogenesis in mouse
gastric cancer. J Biol Chem. 2008 July 11; 283(28): 19864-19871 |
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Cignal™ Reporter Assay System
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Seah C, Levy MA, Jiang Y, Mokhtarzada S, Higgs DR,
Gibbons RJ, Berube NG. Neuronal death resulting from targeted disruption
of the Snf2 protein ATRX is mediated by p53. J. Neurosci., Nov 2008; 28: 12570 - 12580. |
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Sun X, Ritzenthaler JD, Zheng Y, Roman J, Han S.
Rosiglitazone inhibits alpha4 nicotinic acetylcholine receptor
expression in human lung carcinoma cells through peroxisome proliferator-activated
receptor gamma-independent signals. Mol Cancer Ther. 2009
Jan;8(1):110-8. |
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